volume 283, issue 6, PG1320-G1327 2002
DOI: 10.1152/ajpgi.00256.2002
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Abstract: Cell volume regulation plays a vital role in many cell functions. Recent study indicates that both K+ and Cl− channels are important for the regulatory volume decrease (RVD) of cholangiocarcinoma cells, but its physiological significance is unclear due to the tumorous nature of the cells used. This present study reports the RVD of normal mouse cholangiocytes by using freshly isolated bile duct cell clusters (BDCC). A relatively simple and practical method of measuring the cross-sectional area of BDCCs by quan…

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