Janos Luckl, Chao Zhou, Turgut Durduran, Arjun G. Yodh, Joel H. Greenberg
Little information exists on the role and the characteristics of perfusion changes related to periinfarct depolarization. Our aim was to visualize and monitor periinfarct flow transients (PIFTs) in Sprague-Dawley rats (n 5 10) with two different laser methods in a closed-skull model of filament middle cerebral artery occlusion. A laser Doppler probe was placed over the ischemic cortex 5 mm lateral to Bregma, and a 5 3 5 mm area centered 5 mm posterior and 4 mm lateral to Bregma was thinned for laser speckle i…
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