Characterization of OXA-48-like-producing  Enterobacteriaceae  isolated from river water in Algeria

Tafoukt, Rima; Touati, Abdelaziz; Leangapichart, Thongpan; Bakour, Sofiane; Rolain, Jean‐Marc

doi:10.1016/j.watres.2017.04.073

Cited by 58 publications

(38 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This coupled with low awareness on AMU and AMR is likely to further exacerbate the burden of AMR in the region. This review has revealed high prevalence of AMR, including MDR bacteria in the environment, probably associated with anthropogenic activities, application of manure in farming activities and agricultural wastes from community [61,69,85,86]. There is potential spillage of resistant isolates from sewage, humans, companion and domestic animals and industries to the environment [69,87].…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial use and resistance in food-producing animals and the environment: an African perspective

Kimera

Mshana

Rweyemamu

et al. 2020

Antimicrob Resist Infect Control

128

View full text Add to dashboard Cite

Background: The overuse of antimicrobials in food animals and the subsequent contamination of the environment have been associated with development and spread of antimicrobial resistance. This review presents information on antimicrobial use, resistance and status of surveillance systems in food animals and the environment in Africa. Methods: Information was searched through PubMed, Google Scholar, Web of Science, and African Journal Online databases. Full-length original research and review articles on antimicrobial use, prevalence of AMR from Africa covering a period from 2005 to 2018 were examined. The articles were scrutinized to extract information on the antimicrobial use, resistance and surveillance systems.Results: A total of 200 articles were recovered. Of these, 176 studies were included in the review while 24 articles were excluded because they were not relevant to antimicrobial use and/or resistance in food animals and the environment. The percentage of farms using antimicrobials in animal production ranged from 77.6% in Nigeria to 100% in Tanzania, Cameroon, Zambia, Ghana and Egypt. The most antibiotics used were tetracycline, aminoglycoside and penicillin groups. The percentage of multi drug resistant isolates ranged from 20% in Nigeria to 100% in South Africa, Zimbabwe and Tunisia. In the environment, percentage of multi drug resistant isolates ranged from 33.3% in South Africa to 100% in Algeria. None of the countries documented national antimicrobial use and resistance surveillance system in animals. Conclusion:There is high level of antimicrobial use, especially tetracycline, aminoglycoside and penicillin in animal production systems in Africa. This is likely to escalate the already high prevalence of antimicrobial resistance and multi drug resistance in the continent. This, coupled with weak antimicrobial resistance surveillance systems in the region is a great concern to the animals, environment and humans as well.

show abstract

Section: Discussionmentioning

confidence: 99%

Antimicrobial use and resistance in food-producing animals and the environment: an African perspective

Kimera

Mshana

Rweyemamu

et al. 2020

Antimicrob Resist Infect Control

128

View full text Add to dashboard Cite

show abstract

“…50,51 Other Raoultella species were also described as exhibiting OXA-48 carbapenemase. [52][53][54][55] Nonetheless, a few strains of R. ornithinolytica generating simultaneously different types of beta-lactamase (TEM, SHV, KPC and OXA) were described. 42,56 The first case of co-existence of bla KPC-2 and bla IMP-4 carbapenemase genes in the genus Raoultella was reported by Zheng et al (2015) in a 13-year-old male patient with postoperative infection after an orthopedic surgery.…”

Section: Virulence and Resistancementioning

confidence: 99%

<p><em>Raoultella ornithinolytica</em>: Emergence and Resistance</p>

Hajjar¹,

Ambaraghassi²,

Sebajang³

et al. 2020

IDR

View full text Add to dashboard Cite

Raoultella ornithinolytica is an encapsulated Gram-negative, oxidase-negative, catalase-positive, aerobic, non-motile rod that belongs to the Enterobacteriaceae family. This bacterium was initially classified in the genus Klebsiella as Klebsiella ornithinolytica, until the creation of the genus Raoultella in 2001. R. ornithinolytica is usually found in water environments and soil, and due to its ability to convert histidine to histamine, it has been associated with histamine poisoning in humans. R. ornithinolytica is an emerging entity in human infections, with several reports of virulent infections in comorbid at-risk patients. Increasing reports are potentially due to better and more precise identification tools. The objective of this article is to provide a comprehensive review of reported cases of R. ornithinolytica infections, the emergent virulence of described multiresistant strains, and an overview of currently used identification methods.

show abstract

“…Carbapenemase-encoding genes were detected in companion animals, [9][10][11] livestock, 11,12 wild animals, 11,[13][14][15][16] and the environment. 11,17,18 Very few data are available concerning food products, although the New Delhi metallo (NDM)-carbapenemase genes (bla NDM-5 and bla NDM-1 ) have been detected in cows' milk. 12,19 To better characterize the diffusion of CPE in food animals, the aim of this study was to evaluate the presence and the molecular characteristics of these MDR bacteria in chicken meat in Western Algeria.…”

Section: Introductionmentioning

confidence: 99%

Spread of OXA-48 and NDM-1-Producing Klebsiella pneumoniae ST48 and ST101 in Chicken Meat in Western Algeria

Chaalal

Touati

Bakour

et al. 2021

Microbial Drug Resistance

Self Cite

View full text Add to dashboard Cite

We investigated the prevalence of carbapenemase-producing Enterobacteriaceae (CPE) in chicken meat in Western Algeria in 2017. Results: From February to July 2017, samples of chicken meat from three poultry farms in Western Algeria were screened for the presence of CPE. Strains were characterized with regard to antibiotic resistance, blactamase content, Plasmid-mediated quinolone resistance, sulfonamide resistance genes, clonality (repetitive sequence-based profiles and multilocus sequence typing) and virulence traits. Of 181 samples analyzed, 29 (16.0%) carbapenemase-producing Klebsiella pneumoniae were detected. Twenty-three OXA-48-producers (79.3%) and six (20.7%) New Delhi metallo (NDM)-1-producers were observed. Clonality analysis showed three distinct lineages and clonal expansions of the OXA-48-producing K. pneumoniae ST48 and the NDM-1producing K. pneumoniae ST101. These isolates harbored fimH, ureA, mrkD, entB, uge, and wabG. Neither capsular serotype genes nor hypermucoviscous phenotype were detected. Plasmid analysis confirmed that all these isolates harbored the transferable IncL and IncFIIK plasmids. Conclusions: This study reports the spread of OXA-48 and NDM-1-producing K. pneumoniae ST48 and ST101 in chicken meat in Western Algeria and demonstrates that food represents a reservoir of the carbapenemases encoding genes.

show abstract

Characterization of OXA-48-like-producing Enterobacteriaceae isolated from river water in Algeria

Cited by 58 publications

References 42 publications

Antimicrobial use and resistance in food-producing animals and the environment: an African perspective

Antimicrobial use and resistance in food-producing animals and the environment: an African perspective

<p><em>Raoultella ornithinolytica</em>: Emergence and Resistance</p>

Spread of OXA-48 and NDM-1-Producing Klebsiella pneumoniae ST48 and ST101 in Chicken Meat in Western Algeria

Contact Info

Product

Resources

About