2015
DOI: 10.1186/s12917-015-0531-5
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Abstract: BackgroundIsolation of mesenchymal stem cells (MSCs) in equines, has been reported for different tissues including bone marrow, adipose, umbilical cord, peripheral blood, and yolk sac. In regard to the MSCs derived from synovial fluid (SF) or membrane (SM), there is data available for humans, dogs, pigs, goats and horses. Especially in equines, these cells have being considered promising candidates for articular regeneration. Herein, we established and characterized MSCs obtained from equine SF and SM. Samples… Show more

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Cited by 41 publications
(34 citation statements)
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“…Regarding horses, MSCs have been obtained from bone marrow, adipose tissue [5], umbilical cord [68], umbilical cord blood [9], amniotic membrane [10], peripheral blood [11], and recently from synovial fluid (SF) and synovial membrane (SM) [12, 13]. …”
Section: Introductionmentioning
confidence: 99%
“…Regarding horses, MSCs have been obtained from bone marrow, adipose tissue [5], umbilical cord [68], umbilical cord blood [9], amniotic membrane [10], peripheral blood [11], and recently from synovial fluid (SF) and synovial membrane (SM) [12, 13]. …”
Section: Introductionmentioning
confidence: 99%
“…Reports have demonstrated that SFMSCs are multipotent and exhibit properties of adult MSCs; in addition, SF collection is relatively easy and less invasive (17, 18, 26, 29). Studies have reported the isolation, identification, and biological properties of equine SFMSCs and BMMSCs (17, 18, 23, 30).…”
Section: Discussionmentioning
confidence: 99%
“…Synovial fluid ( n  = 5) was obtained using methods described previously (17, 18) with slight modifications. Horses were sedated with detomidine HCl (Pfizer Animal Health, NY, USA) (0.015–0.26 mg/kg bwt i.v.…”
Section: Methodsmentioning
confidence: 99%
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“…They are characterized by an extensive proliferation ability in culture and have the potential to differentiate in vitro into different lineages [5,32,33,36], including adipogenic, chondrogenic, osteogenic [6,29,31,35], myogenic [6,31,35,37], and neurogenic [6,37].…”
Section: Msc Sources Applicable For Musculoskeletal Regenerationmentioning
confidence: 99%