2009
DOI: 10.1590/s1678-91992009000400017 View full text |Buy / Rent full text
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Abstract: ABSTRACT:The main compounds of Bothrops jararaca venom are serine peptidases, metallopeptidases and phospholipases A 2 . These enzymes cause several symptoms, as hemorrhage, coagulation disturbances, edema and myotoxicity. However, effects on smooth muscle are not clear yet. Previous studies in our laboratory have shown that Bothrops jararaca crude venom (CV) provokes contractions of rat vas deferens, followed by relaxation. The aim of this study was to characterize which components of Bothrops jararaca venom … Show more

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