Characterization of Adrenoceptor Types and Subtypes in American Bullfrogs Acclimated to Warm or Cold Temperature

Comparative anatomy of α2 and β adrenoceptors in the adult and developing brain of the marine teleost the red porgy (Pagrus pagrus, Sparidae): [3H]clonidine and [3H]dihydroalprenolol quantitative autoradiography and receptor subtypes immunohistochemistry

“…Even though further work is needed to confirm the applicability of the ␣ 2A /␣ 2C and ␤ 1 /␤ 2 AR terminology in fish, we propose based on our results that ␣ 2A and ␤ 2 AR are predominant in the teleostean brain. With respect to ␣ 2A AR, this is in agreement with results obtained in amphibian (Herman et al, 1996), avian (Dermon and Kouvelas, 1988;FernandezLopez et al, 1997), and some mammalian (DeVos et al, 1992;Ordway et al, 1993;Uhlen et al, 1997) brains. As concerns ␤ AR, our proposal for ␤ 2 AR predominance is in agreement with studies in frog brain (Nahorski, 1978;Herman et al, 1996) and some observations in avian species (Fernandez-Lopez et al, 1997;Revilla et al, 1998) but is contradicted by studies on human and rat brains (Palacios and Kuhar, 1980;Pazos et al, 1985) that pinpoint ␤ 1 as the predominant subtype.…”

“…Our results demonstrate that fish ␣ 2 and ␤ AR have characteristics similar to those of corresponding amphibian (Herman et al, 1996), avian (Dermon and Kouvelas, 1988;Ball et al, 1989;Fernandez-Lopez et al, 1997), and mammalian (Palacios and Kuhar, 1980;Pazos et al, 1985;Unnerstall et al, 1985) receptors. For the first time, a detailed quantitative distribution of ␣ 2 and ␤ AR in developing and adult teleost brain is provided, by using (Unnerstall et al, 1985;Dermon and Kouvelas, 1988;Herman et al, 1996).…”

“…For the first time, a detailed quantitative distribution of ␣ 2 and ␤ AR in developing and adult teleost brain is provided, by using (Unnerstall et al, 1985;Dermon and Kouvelas, 1988;Herman et al, 1996). However, maximal receptor densities (B max ) in most areas were considerably lower than those reported for birds (Dermon and Kouvelas, 1988) and mammals (Palacios and Kuhar, 1980;Unnerstall et al, 1985), in studies with the same ligands.…”

“…it might represent an ancestral ␣ 2 AR subtype (Svensson et al, 1993), highly correlated with a frog ␣ 2 AR (Herman et al, 1996). Moreover, recent cloning and mapping of zebrafish ␣ 2 AR indicates conservation of ␣ 2 AR subtypes across species (Ruuskanen et al, 2004).…”

Sexual dimorphisms in swimming behavior, cerebral metabolic activity and adrenoceptors in adult zebrafish (Danio rerio)

“…Indeed, adrenoceptors are known to display sex dimorphic pattern in brain areas of avian [31,32] and mammalian [33] species. Recent evidence suggests that, zebrafish brain α 2 -and β-ARs [34,35] share similar characteristics with other teleosts [36], amphibians [37], birds [38,39] and mammals [40,41].…”