Characterization of Acinetobacter baumannii genotypes recovered from patients with repeated colonization or infection

Predictability of Doripenem Susceptibility in Acinetobacter baumannii Isolates Based on Other Carbapenem Susceptibilities and blaOXA Gene Status

“…13 Another study evaluating A. baumannii genotypes recovered from patients with repeated colonization or infection found that isolates initially identified as carbapenem resistant were 5.2 times more likely to have closely related isolates obtained from subsequent cultures compared with patients with initial carbapenem-nonresistant isolates. 34 These data indicate that carbapenem-resistant isolates tested in this study are likely from a common PFGE type and are not unique isolates. However, given the insensitivity of PFGE typing to identify unique isolates, it is unclear that such similarity represents horizontal transmission of organisms.…”

“…Isolate genotypes were not assessed in this study; however, existing reports have shown the epidemiology of this species to be clonal in nature, 32,33 particularly when antibiotic resistance exists as shown in previous studies from our own institution. 13,34 Specifically, a study surveying carbapenem-resistant isolates collected from 2004-2007 were typed by pulsed-field gel electrophoresis (PFGE), and 89% and 86% of strains were found to be of the same PFGE type in 2006 and 2007, respectively. 13 Another study evaluating A. baumannii genotypes recovered from patients with repeated colonization or infection found that isolates initially identified as carbapenem resistant were 5.2 times more likely to have closely related isolates obtained from subsequent cultures compared with patients with initial carbapenem-nonresistant isolates.…”

Frequency of Class 1 integron and genetic diversity of Acinetobacter baumannii isolated from medical centers in Kermanshah

“…[2] This organism can be preserved in environment, condition and through pollution levels lead to the spread of infection in hospital. [3] The integrons in A. baumannii isolates, are a mobile genetic elements and they have ability to acquire and expand expressed of the antimicrobial resistance factors. [4] Integrons of Class 1 and 2 are the most recognized integrons that were frequently in A. baumannii and they had resistance with multiple categories to beta-lactams, aminoglycosides, fluoroquinolone and carbapenems.…”

Evaluate the frequency distribution of nonadhesive virulence factors in carbapenemase-producing Acinetobacter baumannii isolated from clinical samples in Kermanshah

“…Acinetobacter baumannii is an aerobic, nonfermentative Gram negative Coccobacillus that can survive for prolonged periods in the environment and can cause nosocomial infections, (urinary tract and wound infections). [ 1 2 3 ] Capability to live under critical circumstances makes it a major pathogen in hospitals. [ 4 ] Extensive use of antimicrobial agents in clinical cases has contributed to the appearance of resistant A. baumannii strains.…”