Characterization, anti-oxidative and anti-inflammatory effects of Costa Rican noni juice (Morinda citrifolia L.)

Dussossoy, Emilie; Brat, Pierre; Bony, Emilie; Boudard, F.; Poucheret, Patrick; Mertz, Christian; Gadrey, Jean; Michel, Alain

doi:10.1016/j.jep.2010.08.063

Cited by 118 publications

(93 citation statements)

References 45 publications

(62 reference statements)

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“…Of these, several phenolic compounds, vitamin C and some lignans were suggested to be responsible for antioxidative activity (Kamiya et al 2004, Su et al 2005, Dussossoy et al 2011, Singh 2012, Saminathan et al 2013, Krishnakumar et al 2015. Furthermore, lipid soluble polyphenols, anthraquinones, α-tocopherol and β-carotene may give rise to part of the antioxidant activity.…”

Section: Discussionmentioning

confidence: 99%

“…Nitric oxide is also involved in carrageenan-induced edema, which reaches its maximum level at 1 h and after that it starts declining (Neha Mohan et al 2013). The study by Dussossoy et al (2011) showed that inhibitory effect of Costa Rican noni juice started at 1 h and lasted for 24 h, and they suggested that noni juice could deal in both the initial and late phases. However, our study assessed antioxidant and anti-inflammatory properties of noni juice at 2nd hour.…”

Section: Discussionmentioning

confidence: 99%

“…As it is well known, these compounds exhibit anti-inflammatory activity through the nitric oxide and prostaglandins E2 pathways (Dussossoy et al 2011, Kokturk et al 2013, Motshakeri and Ghazali 2015.…”

Section: Discussionmentioning

confidence: 99%

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Antioxidant and Anti-inflammatory Activities of a Commercial Noni Juice revealed by Carrageenan-induced Paw Edema

Yilmazer¹,

Coşkun²,

Gürel-Gürevin³

et al. 2016

Polish Journal of Veterinary Sciences

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This study aimed to investigate antioxidant and anti-inflammatory activities of a commercial product of noni (Morinda citrifolia) juice. Carrageenan-induced rat paw edema was employed as inflammatory model. One control and three experimental groups were formed. Experimental groups were administered noni juice alone, noni juice+carrageenan, and carrageenan alone. Oxidant and antioxidant capacity were determined by d-ROMs test and BAP test, respectively. Plasma concentrations of endothelin-1 and leptin were measured by ELISA. Measurements were performed at zero time and 2nd hour of inflammation. Oxidant capacity decreased in noni-received groups at 2nd hour (p=0.019). Antioxidant capacity of the group which received noni alone was found to be higher at 2nd hour (p=0.036). Plasma concentrations of endothelin-1 and leptin were notably lower in noni-received groups (p=0.001 and p=0.021, respectively). The results show that the commercial noni juice investigated has pronounced antioxidant and anti-inflammatory activities.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Antioxidant and Anti-inflammatory Activities of a Commercial Noni Juice revealed by Carrageenan-induced Paw Edema

Yilmazer¹,

Coşkun²,

Gürel-Gürevin³

et al. 2016

Polish Journal of Veterinary Sciences

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“…Furthermore, it also reduced carrageenan induced paw edema, directly inhibited COX-1 and COX-2 activities and inhibited the production of nitric oxide (NO) and prostaglandins E(2) in activated J774 cells, in a dose dependent manner. 22 …”

Section: Ethnobotanical Usementioning

confidence: 99%

Health Benefits of Morinda citrifolia (Noni): A Review

Ali¹,

Kenganora²,

Manjula³

2016

Phcogj

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Background: Morinda citrifolia (Noni) has been used widely as a comple mentary and alternative therapy in many countries owing to its potent anti oxidant activity and proven health benefits. Traditionally, it finds used as a therapeutic remedy to various diseases as an antibacterial, antitumor, anthelminthic, analgesic, anti inflammatory, immunostimulant. Also it has proved beneficial in conditions like gastritis, skin diseases, respiratory infections, menstrual and urinary tract disorders, fever, diabetes and venereal diseases. Objective: This review emphasizes on the phytochemical and mineral profile of the different parts of Noni plant. In addition, this review corroborates the pharmacological basis for the various health benefits, traditional and medicinal applications of Noni. Materials and Methods: All the available information of Noni were collected from electronic databases such as Academic Journals, Ethnobotany, Ethnopharmacology, Springer, PubMed, Google Scholar, Science Direct and other primary and secondary sources. Results: According to our search results pertaining to scientific literature, Morinda citrifolia is used for more than 40 types of ailments worldwide. Crude extract of various parts of plant and fruit juice are reported

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“…É utilizada na medicina tradicional da Polinésia há milênios, no combate a várias doenças, incluindo diabetes, pressão alta e câncer (Chan-Blanco et al, 2006;Bui et al, 2006). Praticamente todas as partes da planta são utilizadas, tais como a raiz, o caule, as folhas e principalmente o fruto (Bui et al, 2006), de onde é extraído o suco, rico em componentes fenólicos, flavonoides, vitamina C e compostos antioxidantes (Dussossoy et al, 2011).…”

Section: Introductionunclassified

Água salina e biofertilizante bovino na produção de frutos e alocação de biomassa em noni (Morinda citrifolia L.)

Souto

Cavalcante

Diniz

et al. 2015

Rev. bras. plantas med.

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RESUMO:Têm sido evidenciado que os compostos orgânicos exercem ação mitigadora dos efeitos tóxicos dos sais às plantas, promovendo maior crescimento e desenvolvimento em solos com excesso de sais. Nessa direção, um experimento foi desenvolvido para avaliar os efeitos do biofertilizante bovino na produção de frutos e alocação de biomassa pelos diversos órgãos de plantas de noni, irrigadas com águas salinas. Os tratamentos foram distribuídos em blocos ao acaso, com quatro repetições e duas plantas por parcela, adotando o arranjo fatorial 5 x 2, correspondente a salinidade das águas de irrigação de 0,5; 1,5; 3,0; 4,5; 6,0 dS m -1 , em substratos sem e com biofertilizante bovino, aplicado uma única vez, em volume correspondente a 10% do volume do substrato, um dia antes da instalação do experimento. As variáveis avaliadas foram: salinidade do solo, expressa pela condutividade elétrica do extrato de saturação do solo; número de frutos; massa média de fruto; produção de frutos por planta; e alocação de biomassa pelas raízes, caules, folhas e frutos. O aumento da salinidade da água de irrigação elevou o caráter salino do solo desde "não salino" para "fortemente salino" e, inibiu a produção de frutos e a acumulação de biomassa seca das plantas de noni em geral, mas, com maior intensidade nos tratamentos sem o insumo orgânico. O biofertilizante estimula o crescimento e a produção de plantas de noni cultivadas sob irrigação com águas de alta salinidade. Palavras-chave:Morinda citrifolia, esterco bovino líquido, salinidade. ABSTRACT: Saline water and bovine biofertilizer on yield and biomass allocation in noni plants (Morinda citrifolia L.).Organic compounds have shown to exercise a mitigating action on salts in plants and they promote growth and development in salt stress environments. In this sense, an experiment was carried out in order to evaluate the effects of saline water irrigation and bovine biofertilizer on yield and biomass allocation by the various organs of noni plants. Treatments were arranged in a randomized block design with four replications and two plants per plot using the 5 x 2 factorial design, which correspond to the salinity levels of irrigation water of 0.5, 1.5, 3.0, 4.5 and 6.0 dS m -1 in substrates with and without bovine biofertilizer, applied to the soil once, in the volume corresponding to 10% of the volume of the substrate one day before the implementation of the experiment. The variables evaluated were soil salinity, expressed as electrical conductivity of the soil saturation extract, fruit number, fruit weight and fruit yield per plant, and biomass allocation by roots, stems, leaves and fruit. The increasing salinity of the water for irrigation increased the saline character of the soil from non-saline to saline soil and inhibited the production and accumulation of dry biomass in noni plants in general but with more intensity in the plants of the treatments without bovine biofertilizer applied to the soil in liquid form. The biofertilizer stimulates the growth and production of noni plants ...

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Characterization, anti-oxidative and anti-inflammatory effects of Costa Rican noni juice (Morinda citrifolia L.)

Cited by 118 publications

References 45 publications

Antioxidant and Anti-inflammatory Activities of a Commercial Noni Juice revealed by Carrageenan-induced Paw Edema

Antioxidant and Anti-inflammatory Activities of a Commercial Noni Juice revealed by Carrageenan-induced Paw Edema

Health Benefits of Morinda citrifolia (Noni): A Review

Água salina e biofertilizante bovino na produção de frutos e alocação de biomassa em noni (Morinda citrifolia L.)

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