Characterization and determination of the major constituents in Belamcandae Rhizoma by HPLC–DAD–ESI-MSn

Zhang, Yuanyuan; Wang, Qi; Qi, Lian‐Wen; Qin, Xiaoying; Qin, Min-Jian

doi:10.1016/j.jpba.2011.05.040

Cited by 66 publications

(48 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, the fragment ion m/z 261.0408 ([M À C 6 H 10 O 5 + H] + ) was derived from the cleavage of glycosidic chain with low abundance in the mass spectrum. The C-glycosidic chain possessed the characteristic of low relative intensity in MS (Beera et al, 2009;Zhang et al, 2011) (Fig. 3).…”

Section: Identification Of Xanthonesmentioning

confidence: 99%

Determination of the chemical constituents of the different processed products of Anemarrhena asphodeloides Rhizomes by high‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry

Peng

Zhao

Lin

et al. 2015

Biomedical Chromatography

View full text Add to dashboard Cite

In this work, high-performance liquid chromatography (HPLC) coupled with a hybrid quadrupole time of-flight mass spectrometry (Q-TOF-MS/MS) was used to study chemical compositions of different processed products of Rhizoma Anemarrhenae (RA). A Grace Alltima(TM) C18 column (250 × 4.6 mm, 5 µm) was used for separation. Mobile phase consisted of 0.1% formic acid and acetonitrile, using gradient elution. ESI-MS data was acquired in both positive and negative mode. The experiment was established on the basis of a series of reference substances (two xanthone and seven saponins) to qualitatively identify the chemical compounds of different processed products of RA by MS analysis. There was no difference in the type of chemical constituents between different processed products of RA. A total of 25 compounds were identified, including four xanthones, 21 steroidal saponins and eight pairs of isomers.

show abstract

Section: Identification Of Xanthonesmentioning

confidence: 99%

Determination of the chemical constituents of the different processed products of Anemarrhena asphodeloides Rhizomes by high‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry

Peng

Zhao

Lin

et al. 2015

Biomedical Chromatography

View full text Add to dashboard Cite

show abstract

“…S. baicalensis is traditionally used for the treatment of inflammation, asthma as well as throat disorders, e.g. cough, tonsillitis and pharyngitis [29]. The combined effects of all these components were thus investigated.…”

Section: Discussionmentioning

confidence: 99%

Anti-inflammatory and antipyretic properties of Kang 601 heji, a traditional Chinese oral liquid dosage form

Alolga¹,

Amadi²,

Onoja³

et al. 2015

Asian Pacific Journal of Tropical Biomedicine

View full text Add to dashboard Cite

Objective: To evaluate the scientific basis for the use of Kang 601 heji (K-601) as an anti-inflammatory and antipyretic agent using appropriate animal models. Methods: Carrageenan-induced rat paw and xylene-induced ear oedemas were models used to investigate anti-inflammatory actions of K-601. Lipopolysaccharide-induced pyrexia model was used to evaluate antipyretic activity in Wistar rats. The antiinflammatory and antipyretic mechanisms were evaluated by detecting prostaglandins E 2 , nitric oxide, interleukin-1b and tumour necrosis factor-a levels using appropriate reagents and ELISA kits. Results: The results revealed that K-601 reduced the level of inflammations in both antiinflammatory models in a dose-dependent manner. The same was true for the antipyretic model. The possible mechanisms of actions were through the inhibition of prostaglandins E 2 , interleukin-1b, tumour necrosis factor-a and nitric oxide. Conclusions: K-601 has proven anti-inflammatory and antipyretic actions. The findings provide a scientific basis for the use of K-601 as anti-inflammatory and antipyretic agent in traditional Chinese medicinal practice.

show abstract

“…LC-UV-MS plays an important role in the screening of phenols and flavonoids. In most cases, ESI-IT-MS n spectral information in conjunction with UV spectra allows rapid identification [69][70][71][72][73][74][75][76][77][78][79][80][81][82][83][84]. The application of TOF-MS in structural elucidation of natural products is of ever increasing interest because TOF mass analyzer with high resolving power can provide the accurate mass measurement and full scan spectral sensitivity [85].…”

Section: Phenols and Flavonoidsmentioning

confidence: 99%

Recent developments in qualitative and quantitative analysis of phytochemical constituents and their metabolites using liquid chromatography–mass spectrometry

Guo

Chen

et al. 2013

Journal of Pharmaceutical and Biomedical Analysis

161

View full text Add to dashboard Cite

Characterization and determination of the major constituents in Belamcandae Rhizoma by HPLC–DAD–ESI-MSn

Cited by 66 publications

References 24 publications

Determination of the chemical constituents of the different processed products of Anemarrhena asphodeloides Rhizomes by high‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry

Determination of the chemical constituents of the different processed products of Anemarrhena asphodeloides Rhizomes by high‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry

Anti-inflammatory and antipyretic properties of Kang 601 heji, a traditional Chinese oral liquid dosage form

Recent developments in qualitative and quantitative analysis of phytochemical constituents and their metabolites using liquid chromatography–mass spectrometry

Contact Info

Product

Resources

About