Changes over time in delivery room management of extremely low birth weight infants in Italy

Equipment for neonatal resuscitation in a middle-income country: a national survey in Vietnam

“…Similar national or local surveys have been previously conducted in high [27–29] as well in low resource settings [30, 31]. These studies aimed to assess the practices of health caregivers and their adherence to official guidelines more than the availability of equipment [27–29].…”

Higher or lower oxygen for delivery room resuscitation of preterm infants below 28 completed weeks gestation: a meta-analysis

“…In the largest study to date, the TO2RPIDO study (ANZ trials registry ACTRN12610001059055)15 recruitment was impeded by clinical bias towards the use of higher FiO 2 10 and recruitment stopped at 15% of projected target numbers (n=1976). However, the TO2RPIDO study found an unexpectedly increased rate of hospital mortality for babies below 28+6 weeks gestation after resuscitation with FiO 2 0.21 when compared with babies resuscitated with FiO 2 1.0.…”

“…As a result, worldwide clinical practice changed considerably within the space of a decade. Currently, clinicians have come to overwhelmingly favour the use of air or lower concentrations of oxygen (<0.3/0.4) when resuscitating both term and preterm infants 10 11…”

Continuous Positive Airway Pressure to Prevent Neonatal Lung Injury: How Did We Get Here, and How Do We Improve?

“…54 In general, prior to randomization, intubated babies had to demonstrate evidence of RDS most frequently quantified as oxygen requirement (40% fraction of inspired oxygen [FiO 2 ]). 54 With increasing use of noninvasive ventilation in the NICU, 55,56 it became unclear what cut-offs should be used to define "CPAP failure" and trigger surfactant therapy. Many clinicians still use an oxygen requirement of 40%, with a mean airway pressure (or Paw) of 6-7 cm H 2 O to define CPAP failure and trigger surfactant therapy.…”