Changes in sow milk lipidome across lactation occur in fatty acyl residues of triacylglycerol and phosphatidylglycerol lipids, but not in plasma membrane phospholipids

Suárez-Trujillo, Aridany; Luecke, Sarah M; Logan, Lea; Bradshaw, Christina V; Stewart, Kara R; Minor, Radiah C.; Ferreira, Christina R.; Casey, Theresa

doi:10.1016/j.animal.2021.100280

Cited by 13 publications

(14 citation statements)

References 51 publications

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“…Recently, Suarez-Trujillo et al [49] demonstrated the maturational changes in the lipid fractions of colostrum, transitional and mature milk. Specifically, mature milk contained higher levels of triacylglycerides and phosphatidylglycerols compared to colostrum (day 0) and transitional (days 3 and 7) and mature milk (day 14) [50]. Moreover, the carbon chain length and the unsaturation within the fatty acyl residues decreased from day 0 to 14 in both triglycerides and phosphatidylglycerols in their study [50].…”

Section: Lipid Composition Of Porcine Colostrum and Milkmentioning

confidence: 88%

“…Regarding the other main lipid classes, cholesterol was the main sterol found in swine colostrum (~96% of total sterols) in the study of Luise et al [48], while traces of sitosterol and campesterol have been also reported for porcine milk and milk from other species [51,52]. Moreover, porcine milk fat contains SCFA at barely detectable levels [50], thereby mirroring their concentration in serum. Porcine milk stimulates fermentation and thus increases SCFA and certain MCFA in the gastrointestinal tract of piglets due to their large amounts of disaccharides and oligosaccharides [53].…”

Section: Lipid Composition Of Porcine Colostrum and Milkmentioning

confidence: 98%

“…Specifically, mature milk contained higher levels of triacylglycerides and phosphatidylglycerols compared to colostrum (day 0) and transitional (days 3 and 7) and mature milk (day 14) [50]. Moreover, the carbon chain length and the unsaturation within the fatty acyl residues decreased from day 0 to 14 in both triglycerides and phosphatidylglycerols in their study [50]. Against popular belief, porcine colostrum and milk consist only to about 30% of saturated medium-chain FAs, whereas the other two-thirds consists of 30% of monounsaturated long-chain FAs and 30% of PUFAs [47,48].…”

Section: Lipid Composition Of Porcine Colostrum and Milkmentioning

confidence: 98%

“…Against popular belief, porcine colostrum and milk consist only to about 30% of saturated medium-chain FAs, whereas the other two-thirds consists of 30% of monounsaturated long-chain FAs and 30% of PUFAs [47,48]. The main FAs are palmitic acid (C16:0), oleic acid (C18:1) and LA (C18:2), representing about 80% of the FAs in porcine colostrum and milk [48][49][50][51]. Notably, the colostrum contains higher proportions of C18:2 n-6, C20:4 n-6, C20:5 n-3, C22:5 n-3, C22:6 n-3 than transition and mature milk [49], supporting their importance for early postnatal development of the piglets.…”

Section: Lipid Composition Of Porcine Colostrum and Milkmentioning

confidence: 99%

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The Role of Dietary and Microbial Fatty Acids in the Control of Inflammation in Neonatal Piglets

Metzler‐Zebeli

2021

Animals

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Excessive inflammation and a reduced gut mucosal barrier are major causes for gut dysfunction in piglets. The fatty acid (FA) composition of the membrane lipids is crucial for mediating inflammatory signalling and is largely determined by their dietary intake. Porcine colostrum and milk are the major sources of fat in neonatal piglets. Both are rich in fat, demonstrating the dependence of the young metabolism from fat and providing the young organism with the optimum profile of lipids for growth and development. The manipulation of sow’s dietary polyunsaturated FA (PUFA) intake has been shown to be an efficient strategy to increase the transfer of specific FAs to the piglet for incorporation in enteric tissues and cell membranes. n-3 PUFAs, especially seems to be beneficial for the immune response and gut epithelial barrier function, supporting the piglet’s enteric defences in situations of increased stress such as weaning. Little is known about microbial lipid mediators and their role in gut barrier function and inhibition of inflammation in neonatal piglets. The present review summarizes the current knowledge of lipid nutrition in new-born piglets, comparing the FA ingestion from milk and plant-based lipid sources and touching the areas of host lipid signalling, inflammatory signalling and microbially derived FAs.

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Section: Lipid Composition Of Porcine Colostrum and Milkmentioning

confidence: 88%

Section: Lipid Composition Of Porcine Colostrum and Milkmentioning

confidence: 98%

Section: Lipid Composition Of Porcine Colostrum and Milkmentioning

confidence: 98%

Section: Lipid Composition Of Porcine Colostrum and Milkmentioning

confidence: 99%

See 2 more Smart Citations

The Role of Dietary and Microbial Fatty Acids in the Control of Inflammation in Neonatal Piglets

Metzler‐Zebeli

2021

Animals

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“…Phosphatidylglycerol is a precursor for cardiolipin (CL), which is an inner mitochondrial membrane lipid (Stillwell, 2016). Therefore, the presence of PG in the colostrum may be reflective of lactocyte mitochondria being secreted into milk, which has been suggested in sow milk (Suarez-Trujillo et al, 2021). Because colostrum composition likely reflects the calf's requirements and mitochondria generate 90% of a cell's energy, high levels of PG substrates may be needed to support mitochondrial biogenesis in cells of growing tissues.…”

Section: Discussionmentioning

confidence: 98%