Abstract:Adult neural stem cells (NSCs) are neural progenitor cells that differentiate into neurons and glial cells in the brain throughout an organism’s life. The sub ventricular zone(SVZ) in mammals holds a niche of NSCs that are involved in neurologic plasticity, brain damage repair, behavioral response to stimuli, and learning and memory formation. Cultured SVZ-derived NSCs offer an accessible model for investigating the cellular and molecular mechanisms in brain function.Manganese causes neuronal dysfunction, but … Show more
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