Changes in Corneal Endothelial Cells after Ahmed Glaucoma Valve Implantation: 2-Year Follow-up

Lee, Eun‐Kyoung; Yun, Yong-Jun; Lee, Jong-Eun; Yim, Jin-Ho; Kim, Chang Sik

doi:10.1016/j.ajo.2009.04.016

Cited by 139 publications

(118 citation statements)

References 18 publications

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“…Lee et al. (2009) found an ECD decrease of 22.6% in the superotemporal quadrant (closest to the Ahmed tube) at 24 months. The peripheral EC loss after 24 months was 13.14% in our study.…”

Section: Discussionmentioning

confidence: 96%

“…2009), in which EC loss in eyes with an Ahmed glaucoma tube in the anterior chamber was studied. In their paper, a mean central EC loss of 15.4% was found 24 months after the implantation of an Ahmed glaucoma valve S2.…”

Section: Discussionmentioning

confidence: 99%

“…(2009) Their mean follow‐up time was 19 months, whereas our subjects were followed for 36 months. Furthermore, the TC distance was not taken into account in their study.…”

Section: Discussionmentioning

confidence: 99%

“…2009; Lee et al. 2009). In cases of corneal decompensation, the central corneal thickness (CCT) was increased.…”

Section: Introductionmentioning

confidence: 99%

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Corneal endothelial cell loss after Baerveldt glaucoma drainage device implantation in the anterior chamber

Tan

Webers

Berendschot

et al. 2016

Acta Ophthalmologica

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PurposeTo investigate central and peripheral corneal endothelial cell density (ECD) in relation to Baerveldt (BV) glaucoma drainage device (GDD) tube corneal (TC) distance.MethodsProspective study of all patients scheduled for glaucoma tube surgery with 36 months follow‐up. A BV GDD was inserted into the anterior chamber (AC). Anterior segment optical coherence tomography (AS‐OCT) scans were made to determine the TC distance. Central and peripheral ECD was measured, preoperatively and at 3, 6, 12, 24 and 36 months postoperatively.ResultsFifty‐three eyes were included [primary open‐angle glaucoma, (n = 13); secondary glaucoma, (n = 30); and primary angle‐closure glaucoma, (n = 10)]. Central ECD significantly decreased during follow‐up, with a mean decrease of 4.54% per year (p < 0.001), and 6.57% in the peripheral quadrant closest to the BV GDD tube (PQC, p < 0.001). In the PQC, a yearly decrease of 1.57% was shown after transiridial tube placement versus 7.43% after placement ‘free’ into the AC (p = 0.006). Endothelial cell (EC) loss was related to TC distance (mean 1.69 mm), with a central loss of 6.20% and 7.25% in the PQC per year with shorter TC distances, versus a central loss of 4.11% and 5.77% in the PQC per year with longer TC distances (outside mean ± 2SD, p < 0.001). A difference in EC loss by glaucoma subtype was not identified.ConclusionThe TC distance is of significant influence on corneal ECD, a shorter TC distance causing more severe EC loss, especially in the PQC. Transiridial placement of the BV GDD tube seems safer than placement ‘free’ into the AC.

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“…Lee et al. (2009) found an ECD decrease of 22.6% in the superotemporal quadrant (closest to the Ahmed tube) at 24 months. The peripheral EC loss after 24 months was 13.14% in our study.…”

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Corneal endothelial cell loss after Baerveldt glaucoma drainage device implantation in the anterior chamber

Tan

Webers

Berendschot

et al. 2016

Acta Ophthalmologica

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“…The presence of a tube in the anterior chamber is known to disturb the normal environment of the corneal endothelium. 6 Previous reports have found corneal decompensation to be the main complication following a second GDI procedure. [2][3][4][5] Another viable procedure option if extra drainage is needed is to add a second GDI piggybacked to the primary GDI bleb, that is, without actually entering the anterior chamber again.…”

Section: Introductionmentioning

confidence: 99%

Insertion of sequential glaucoma drainage implant in a piggyback manner

Välimäki

2015

Eye

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Purpose This pilot study, the first of its type, was conducted to determine the clinical outcome of a sequential glaucoma drainage implant (GDI) inserted in piggyback manner, that is into the bleb of a primary GDI. Methods This was a retrospective chart study with a minimum 1-year follow-up involving 16 eyes of 14 uncontrolled glaucoma patients who had previously undergone sequential GDI performed using a technique to convert a one-plate into a two-plate implant system. Surgical success was defined as intraocular pressure (IOP) o21 mm Hg with at least a 30% reduction in IOP from baseline on two consecutive follow-up visits, IOP 45 mm Hg on two consecutive follow-up visits, and neither reoperation of glaucoma nor loss of light perception vision. Results The mean ± SD baseline IOP was 29.2 ± 5.2 mm Hg, and the mean postoperative IOP was 17.3 ± 3.4 mm Hg, with a mean pressure drop of 39.4 ± 10.4% (Po0.001). Life-table analysis showed an 88% success rate after 12 months of follow-up. The mean preoperative best corrected visual acuity (BCVA) was 0.2 ± 0.2 logMAR (Snellen equivalent 6/9.5), compared with 0.3 ± 0.3 logMAR postoperatively (Snellen equivalent 6/12; P = 0.497). Postoperative complications included a flat anterior chamber and choroidal detachment (one eye), uveitis and cataract (one eye), diplopia (one eye), and worsening of pre-existing pseudophakic bullous keratopathy (one eye). Conclusions In glaucoma eyes with useful vision the piggyback GDI seems to provide a significant IOP lowering with minimal complications in patients in whom an initial GDI had failed to control the IOP.

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Baseline Factors Related to Endothelial Cell Loss Following Penetrating Keratoplasty

et al. 2011

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Changes in Corneal Endothelial Cells after Ahmed Glaucoma Valve Implantation: 2-Year Follow-up

Cited by 139 publications

References 18 publications

Corneal endothelial cell loss after Baerveldt glaucoma drainage device implantation in the anterior chamber

Corneal endothelial cell loss after Baerveldt glaucoma drainage device implantation in the anterior chamber

Insertion of sequential glaucoma drainage implant in a piggyback manner

Baseline Factors Related to Endothelial Cell Loss Following Penetrating Keratoplasty

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