Changes in blood glucose and insulin after an oral palatinose administration in normal subjects.

Kawai, Koichi; Okuda, Yukichi; Yamashita, Kamejiro

doi:10.1507/endocrj1954.32.933

Cited by 92 publications

(69 citation statements)

References 6 publications

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“…Viscosities of aqueous solutions and organoleptic properties of these sugars are quite similar to that of sucrose (Mattes et al 1998). In addition hereto, toxicity analysis revealed that isomaltulose and trehalulose, as sucrose, are non-toxic (Kawai et al 1985;Jonker et al 2002). As concerns their physicochemical properties, these sucrose isomers appear adequate for substitution of sucrose in mainly sweet foods.…”

Section: Properties and Production Of Isomaltulose And Trehalulosementioning

confidence: 89%

“…Interestingly, isomaltulose and trehalulose are hardly fermented and less rapidly cleaved in the small intestine than sucrose. This causes an attenuated blood glucose and insulin response, a property which is very attractive for diabetics (Kawai et al 1985;Yamada et al 1985). It is worth noting that pH-telemetry studies, which are the internationally recognized standard for tooth-friendly claims, proved the non-cariogenicity of palatinose (isomaltulose) ; trehalulose being also reported to be "tooth friendly" (Hamada 2002).…”

Section: Properties and Production Of Isomaltulose And Trehalulosementioning

confidence: 99%

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Bacterial sucrose isomerases: properties and structural studies

Rhimi

Haser²,

Aghajari³

2008

Biologia

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Due to their significant role in food industry, sucrose isomerases are good candidates for rational protein engineering. Hence, specific modifications in order to modify substrate affinity and selectivity, product specificity but also to adapt their catalytic properties to particular industrial process conditions, is interesting. Our work on the structural studies of the sucrose isomerase, MutB, which presents the first structural data available on a trehalulose synthase and the first experimental data on complexed forms of sucrose isomerases represents a significant advance in the understanding of these enzymes. In this review we give an overview of what is known on biochemical properties and structural aspects of different sucrose isomerases in particular those reported from bacteria.

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Section: Properties and Production Of Isomaltulose And Trehalulosementioning

confidence: 89%

Section: Properties and Production Of Isomaltulose And Trehalulosementioning

confidence: 99%

Bacterial sucrose isomerases: properties and structural studies

Rhimi

Haser²,

Aghajari³

2008

Biologia

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“…The rats were placed in the chamber immediately after the oral administration of [1-13 C]sucrose or [1][2][3][4][5][6][7][8][9][10][11][12][13] C]palatinose at a dose of 2 g/kg (mixture of 0·175 g of [1- Schematic illustration of the system used to collect expired air from rats. Briefly, this system composed of a desiccator that was used as an animal chamber, a pump and breath sampling bags.…”

Section: C-breath Testmentioning

confidence: 99%

Studies on absorption and metabolism of palatinose (isomaltulose) in rats

Tonouchi¹,

Yamaji²,

Uchida³

et al. 2010

Br J Nutr

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We evaluated the absorption and metabolism of palatinose in rats by the carbohydrate load test and the 13 C-and H 2 -breath tests. We compared the results of these tests with those of sucrose, since sucrose is an isomer of palatinose and generally known to be degraded and absorbed from the small intestine. In the carbohydrate load test, blood glucose and plasma insulin levels after oral administration of palatinose rose more gradually and reached a maximum that was lower than that after sucrose administration. C fru ] showed no difference between palatinose and sucrose. In the H 2 -breath test, the concentration of H 2 in the expired air was measured for 420 min. H 2 was hardly detected with both palatinose and sucrose and no significant difference was observed between the two groups. These results suggest that palatinose is utilised in vivo at a rate equal to that of sucrose.

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“…Kawai et al 85 investigaram e compararam a concentração de glicose e insulina no plasma em resposta à ingestão de isomaltulose e sacarose. O nível de glicose no plasma aumentou gradualmente e atingiu um máximo de 110,9 mg/dL após 60 min, quando se administraram 50 g de isomaltulose, permanecendo no mesmo nível após 120 min.…”

Section: Propriedades Nutrição E Metabolismo Da Isomaltuloseunclassified

Produção de isomaltulose, um substituto da sacarose, utilizando glicosiltransferase microbiana

Kawaguti¹,

Sato²

2008

Quím. Nova

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Changes in blood glucose and insulin after an oral palatinose administration in normal subjects.

Cited by 92 publications

References 6 publications

Bacterial sucrose isomerases: properties and structural studies

Bacterial sucrose isomerases: properties and structural studies

Studies on absorption and metabolism of palatinose (isomaltulose) in rats

Produção de isomaltulose, um substituto da sacarose, utilizando glicosiltransferase microbiana

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