CFD analysis of flow distributor designs for numbering-up of biodiesel synthesis

Lopes, Mariana Garcia Mendonça; Santana, Harrson Silva; Andolphato, Vinícius Felix; Silva, João Lameu; Taranto, Osvaldir Pereira

doi:10.1016/j.cherd.2018.09.011

“…[2], [3] and the discussion of them contributed to the presentation in the present form. The data of CDO13, CDO52 and CD26 were present in article CFD analysis of flow distributor designs for numbering-up of biodiesel synthesis [1].…”

Section: Datamentioning

confidence: 99%

“…For the simulation analysis the CDO52, CDO13 and CD26 designs were evaluated (CFD analysis of flow distributor designs for numbering-up of biodiesel synthesis [1]). …”

Section: Datamentioning

confidence: 99%

Flow uniformity data on 3D printed flow distributors

Lopes

¹

,

Santana

²

,

Andolphato

³

et al. 2019

Data in Brief

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Micro-chemical plants are chemical plants that use micrometrics structures by performing a numbering-up of microdevices. The flow distributor is responsible for the uniform distribution through these microdevices. Inadequate designs reduce the plant performance. Thus, 3D printing is a good alternative to allow fast and economic development for design tests. The present research applied 3D printing to manufacture flow distributors and evaluated the flow uniformity from experimental tests. This data article presents values of the non-uniformity flow coefficient (Ф) of three distinct distributors: the rectangular distributor (RD), the conical distributors with obstacle (CDO) and the conical distributor without obstacle (CD). The distributors were tested in water flow and at low flow rates, it was observed a flow maldistribution, related to the presence of air bubbles. For high flow rates the Ф reduced to values below 1%. The results presented here were used to validate the numerical simulations of flow distributors for numbering-up of biodiesel synthesis in micro and millidevices, “CFD analysis of flow distributor designs for numbering-up of biodiesel synthesis” [1].

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“…Recent researches approached additional efforts for numbering-up procedure, e.g., flow rate distribution at each microdevice parallelized in the chemical plant [11]. For instance, considering a biodiesel plant with a capacity of 2000 L day -1 [12], 3.4 x 10 6 microreactor units operating at 5.8 × 10 -4 L min -1 would be necessary [13].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Reaction Between 2,4-Thiazolidinedione and P-Methoxybenzaldehyde in Microreactors for Production of Drugs for Treatment of Diabetes Mellitus Type 2

Vieira¹,

Santana

²

,

Silva³

et al. 2020

Preprint

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The use of microreactors in chemical and pharmaceutical industries allow a series of advantages due to their reduced sizes regarding conventional batch reactors. In the present paper the transposition of the reaction between 2,4-Thiazolidinedione with p-Methoxybenzaldehyde, generating the compound with potential biological action against diabetes mellitus type II, from batch to a continuous capillary microreactor was carried out. The microdevice performance was evaluated experimentally and numerically by Computational Fluid Dynamics. The efficiency and viability of microreactors usage for the intermediate pharmaceutical active production was assessed. The optimized operating conditions were obtained for the batch reactor (processing time) and microreactor (residence time), the promoter base selection and optimal concentration was also performed, in order to maximize reactants conversion and reaction yield. Considering the acquired data, computational fluid dynamic simulations were carried out, allowing obtaining a computational methodology to be used for a fast increment of production from microreactor to industrial demand.

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“…Recent researches approached additional efforts for numbering-up procedure, e.g., flow rate distribution at each microdevice parallelized in the chemical plant [11]. For instance, considering a biodiesel plant with a capacity of 2000 L day -1 [12], 3.4 x 10 6 microreactor units operating at 5.8 × 10 -4 L min -1 would be necessary [13].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Reaction Between 2,4-Thiazolidinedione and P-Methoxybenzaldehyde in Microreactors for Production of Drugs for Treatment of Diabetes Mellitus Type 2

Vieira¹,

Santana²,

Silva³

et al. 2020

Preprint

Self Cite

0

View full text Add to dashboard Cite

The use of microreactors in chemical and pharmaceutical industries allow a series of advantages due to their reduced sizes regarding conventional batch reactors. In the present paper the transposition of the reaction between 2,4-Thiazolidinedione with p-Methoxybenzaldehyde, generating the compound with potential biological action against diabetes mellitus type II, from batch to a continuous capillary microreactor was carried out. The microdevice performance was evaluated experimentally and numerically by Computational Fluid Dynamics. The efficiency and viability of microreactors usage for the intermediate pharmaceutical active production was assessed. The optimized operating conditions were obtained for the batch reactor (processing time) and microreactor (residence time), the promoter base selection and optimal concentration was also performed, in order to maximize reactants conversion and reaction yield. Considering the acquired data, computational fluid dynamic simulations were carried out, allowing obtaining a computational methodology to be used for a fast increment of production from microreactor to industrial demand.

show abstract

CFD analysis of flow distributor designs for numbering-up of biodiesel synthesis

Cited by 14 publications

References 22 publications

Flow uniformity data on 3D printed flow distributors

Flow uniformity data on 3D printed flow distributors

Evaluation of Reaction Between 2,4-Thiazolidinedione and P-Methoxybenzaldehyde in Microreactors for Production of Drugs for Treatment of Diabetes Mellitus Type 2

Evaluation of Reaction Between 2,4-Thiazolidinedione and P-Methoxybenzaldehyde in Microreactors for Production of Drugs for Treatment of Diabetes Mellitus Type 2

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