Cervical fetal fibronectin in patients at increased risk for preterm delivery

Bittar, Roberto Eduardo; Yamasaki, Arlete Ayako; Sasaki, Solange; Zugaib, Marcelo

doi:10.1016/s0002-9378(96)70271-5

Cited by 47 publications

(27 citation statements)

References 9 publications

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“…The fetal membrane must bear the load of pressure from amniotic fluid and repetitive minor loads, such as Braxton-hicks contractions, during gestation [80]. The mechanical strength of this membrane makes it an attractive scaffold to be used as surgical graft.…”

Section: Mechanical Propertiesmentioning

confidence: 99%

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

et al. 2010

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Section: Mechanical Propertiesmentioning

confidence: 99%

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

et al. 2010

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“…O parto pré-termo (PPT), ou seja, o que ocorre antes da 37ª semana completa, constitui importante determinante da morbidade neonatal e infantil, incluindo alterações do desenvolvimento neuro-motor, doenças respiratórias crônicas, predisposição para processos infecciosos e distúr-bios oftalmológicos 3 . Muitas publicações destacam métodos clínicos, marcadores biológicos, bioquímicos e ultrasonográficos que, aplicados isolada ou combinadamente, buscam predizer o PPT espontâ-neo 1,[4][5][6] . O exame ultra-sonográfico transvaginal (US-TV) é o método mais eficaz para o estudo do colo uterino durante a gravidez e permite avaliar a morfologia e a biometria cervical com alto grau de confiabilidade 7 .…”

Section: Trabalhos Originaisunclassified

Avaliação da medida do comprimento do colo e da ausência do eco glandular endocervical para predição do parto pré-termo

Pires¹,

Moron²,

Mattar³

et al. 2004

Rev. Bras. Ginecol. Obstet.

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“…Metaregression analysis showed that the accuracy of the test did not depend on the method of testing, how often the test was done, or classification of risk. As for asymptomatic women, the accuracy of the in predicting sponGarcia (1999) 71 Greenhagen (1996) 72 Di Stefano (1999) 27 Zamora (2000) 73 Chang (1997) 25 Roubille (1999) 84 Nageotte (1994) 66 Nageotte (1994) 66 Bittar (1996) 23 Bittar (1996) 23 Nageotte (1994) 66 Oliveira (1998) 67 Nageotte (1994) 66 Leeson (1996) 61 Leeson (1996) 61 Krems (1995) 69 Goldenberg (2000) 77 Lockwood (1993) 80 Tolino (1996) 41 Lockwood (1993) 80 Tolino (1996) 41 Goldenberg (1997) 76 Wennerholm (1997) 94 Goldenberg (1996) 75 Hellemans (1995) 43 Crane (1999) 44 Faron (1997) 42 Hux (1995) 78 Inglis (1994) 79 Crane (1999) 44 Vercoustre (1996) Figure 9 shows the summary receiver operating characteristic curve for symptomatic women. Figures 10, 11, and 12 give details of individual results used to create the summary curve.…”

Section: Fibronectin Test In Symptomatic Womenmentioning

confidence: 99%

Accuracy of cervico-vaginal fetal fibronectin test in predicting the risk of spontaneous preterm birth—a systematic review

Honest

Bachmann²,

Kleijnen³

et al. 2003

Journal of Obstetrics and Gynaecology

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Objective To determine the accuracy with which a cervicovaginal fetal fibronectin test predicts spontaneous preterm birth in women with or without symptoms of preterm labour. Design Systematic quantitative review of studies of test accuracy. Data sources Medline, Embase, PASCAL, Biosis, Cochrane Library, Medion, National Research Register, SCISEARCH, conference papers, manual searching of bibliographies of known primary and review articles, and contact with experts and manufacturer. Study selection Two reviewers independently selected and extracted data on study characteristics, quality, and accuracy. Data extraction Accuracy data were used to form 2×2 contingency tables with spontaneous preterm birth before 34 and 37 weeks' gestation and birth within 7-10 days of testing (for symptomatic pregnant women) as reference standards. Data were pooled to produce summary receiver operating characteristic curves and summary likelihood ratios for positive and negative test results. Data synthesis 64 primary articles were identified, consisting of 28 studies in asymptomatic women and 40 in symptomatic women, with a total of 26 876 women. Among asymptomatic women the best summary likelihood ratio for positive results was 4.01 (95% confidence interval 2.93 to 5.49) for predicting birth before 34 weeks' gestation, with corresponding summary likelihood ratio for negative results of 0.78 (0.72 to 0.84). Among symptomatic women the best summary likelihood ratio for positive results was 5.42 (4.36 to 6.74) for predicting birth within 7-10 days of testing, with corresponding ratio for negative results of 0.25 (0.20 to 0.31). Conclusion Cervicovaginal fetal fibronectin test is most accurate in predicting spontaneous preterm birth within 7-10 days of testing among women with symptoms of threatened preterm birth before advanced cervical dilatation.

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Cervical fetal fibronectin in patients at increased risk for preterm delivery

Cited by 47 publications

References 9 publications

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

Avaliação da medida do comprimento do colo e da ausência do eco glandular endocervical para predição do parto pré-termo

Accuracy of cervico-vaginal fetal fibronectin test in predicting the risk of spontaneous preterm birth—a systematic review

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