A 23 years old female presented on 29th April 2013, with complaints of fever of 3 months duration, seizures and altered sensorium for one week. Fever was low grade (up to 100º F), intermittent, and not associated with chills and rigors and subsided with medication. The patient had generalized tonic clonic seizures since 7 days and had nine episodes of seizures in 4 hours and altered sensorium since then. The altered sensorium was in the form of unresponsiveness to verbal commands, not recognizing relatives and was associated with uprolling of eyeballs and tongue-bite. The patient had a background history of single episode of seizure, three and half months back, 3 hours postpartum. The antenatal period was uneventful, and she delivered a live male baby. She was managed conservatively and discharged in the postpartum period. She had no history of headache, vomiting, blurring of vision, trauma, cough, shortness of breath, chest pain, jaundice, abdominal pain, joint pains, rashes and bleeding tendencies, loss of appetite RU ORVV RI ZHLJKW 1R RWKHU VLJQL¿FDQW IDPLO\ KLVWRU\ ZDV obtained. On general physical examination, she presented with fever, hypotension (90/70 mm of Hg), tachycardia (170/minute and feeble) and respiratory distress (respiratory rate 40/minute and gasping) with Glasgow coma scale *&6 RI (09 DQG GROO ¶V H\H UHÀH[ ZDV DEVHQW Systemic examination revealed signs of meningism in the form of neck-rigidity and Kernig's sign was positive, EUDLQ VWHP UHÀH[HV ZHUH DEVHQW SXSLOV ZHUH ELODWHUDOO\ small and sluggishly reacting. The muscle tone and bulk were normal, power could not be assessed, deep tendon UHÀH[HV ZHUH LQ ELODWHUDO XSSHU DQG ORZHU OLPEV 7KH bilateral plantar reÀHxes were mute. Rest of the systemic examination was within normal limit. Investigations revealed anemia (predominantly normocytic and normochromic with few microcytes), raised ESR (60 mm), transaminitis (SGOT-581/ul, SGPT-129/ul, alkaline phosphatase-279/ul), hypoalbuminemia (albumin 2.1 g/dl), and raised serum creatinine (2.19 mg/dl). The coagulogram showed prolonged PT (21 seconds; control 14 seconds), aPTT (39 seconds; control 32 seconds) and deranged prothrombin index (PTI) (66%) and International normalized ratio (INR) +RZHYHU WKH ¿EULQRJHQ ZDV QRUPDO DQG 'GLPHU was present. CSF analysis revealed increased cells, initially polymorphs (10 cells/ul) and later lymphocytic pleocytosis (70 cells/ul) with low sugar (29 mg/dl), high protein (152 mg/dl) and ADA of 20 U/L. Gram stain, cryptola and TB-3&5 LQ FHUHEURVSLQDO ÀXLG &6) ZHUH DOO QHJDWLYH 5RXWLQH urine analysis revealed trace amount of albumin, no sugar, 3-5 pus cells/hpf and no Red blood cells (RBCs). Blood culture and endotracheal tube aspirate cultures were