Cerebellar ataxia in enteric fever.

Abstract

SUMMARY In a study of enteric fever, cerebellar ataxia was found to be the commonest neurological manifestation, second only to toxic delirium. Excluding toxic delirium (found in 25-30% of cases) neurologic deficit was noted in 5-0% of a series of 718 consecutive cases; 2-3% showed cerebellar ataxia, either as an isolated feature or in association with other lesions. The ataxia usually appeared in the second week, and lasted a mean of 9-4 days. In 90% of cases it had cleared completely within a month.

Typhoid Fever Presenting as Acute Psychosis

“…1% had peripheral neuropathy, mononeuritis multiplex and late development of post typhoidal schizophreniform psychosis. RS Wadia et al [5]. have reported cerebellar ataxia as the commonest neurological complication of enteric fever among the 28 cases that they had studied, The ataxia was the sale feature in lOaf the cases, while in the other 18 it was associated with other neurological manifestations.…”

“…However. detailed serological analysis and autopsy studies of patients who died following typhoid with neurological manifestations has failed to provide any evidence to support any of the above causes and it yet remains elusive [4,5,8]. In conclusion, patients presenting with acute onset fever and abnormal behaviour in tropical countries, like our patient, should also be evaluated for typhoid fever in addition to other diseases like encephalitis, cerebral malaria etc.…”

“…Though neuropsychiatric complications are reported in as much as 45-76% of patients during every stage of typhoid fever [4][5][6][7][8], the chance of misdiagnosis or delayed diagnosis of the primary illness is still quite common. Most of such cases are considered to be a part of the "Typhoid toxaemia", where patients develop delirium and confusion during the initial stages of the disease along with high fever, and generally subsides within 1-2 days ofdefervescence [8].…”

Isolated cerebellar ataxia: an early neurological complication of enteric fever

“…Neurological involvement in enteric fever has a wide spectrum of presentation. [4][5][6] Meningism and delirium are the common neurological manifestations. Acute cerebellar ataxia as a lone neurological manifestation of enteric fever is very rare.…”

Salmonella Encephalopathy with Seizure and Frontal Intermittent Rhythmic Delta Activity

“…Encephalopathy, coma, meningitis, transient Parkinsonism, motor neurone disorder, seizure, cerebellitis, peripheral neuropathy and Guillain-Barré syndrome have been reported to accompany typhoid fever [1][2][3][4][5][6][7][8].…”