2003
DOI: 10.1001/jama.289.13.1659
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Cereal, Fruit, and Vegetable Fiber Intake and the Risk of Cardiovascular Disease in Elderly Individuals

Abstract: URRENTLY 35 MILLION PERsons aged 65 years or older live in the United States, accounting for nearly 13% of the population. 1 These older adults are the fastest-growing segment of the population, and by 2030, it is projected that 70 million persons, or 1 in every 5, will be 65 years old or older. 1 Cardiovascular disease (CVD) is the leading cause of death and disability among these older adults, who also account for a disproportionately large share of the $200 billion annual US health care expenditures for CVD… Show more

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Cited by 267 publications

(189 citation statements)
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“…The inverse associations of fruit and cereal fiber intakes, but not vegetable fiber intake, with mortality from CHD in the present study were consistent with findings from previous studies: the Women's Health study (23), Nurse Health study (24), Cardiovascular Health Study (25), and the pooled analysis of 10 American and European cohort studies (7).…”
Section: Discussionsupporting
confidence: 92%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The inverse associations of fruit and cereal fiber intakes, but not vegetable fiber intake, with mortality from CHD in the present study were consistent with findings from previous studies: the Women's Health study (23), Nurse Health study (24), Cardiovascular Health Study (25), and the pooled analysis of 10 American and European cohort studies (7).…”
Section: Discussionsupporting
confidence: 92%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…However, the association was no longer significant after further adjustment for intake of cold cereal, which is in agreement with our observations. The attenuation of measures of association after adjustment for cold cereal or whole grains in general suggests that results were confounded by the generally favorable association of these foods on CVD and its risk factors (36,37). Overall, our findings are consistent with previous epidemiological studies evaluating the main food sources of Mg, nonheme iron, and other suspected antioxidant micronutrients.…”
Section: Discussionsupporting
confidence: 87%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Cereal fiber by itself had the least influence on CHD risk (RR 0.90; 95% CI, 0.80–1.01). A similar finding was made by Mozaffarian et al [ 60 ]. After adjustment for potential confounders, the overall reduction in CVD risk from consumption of cereal fiber was 14% (HR 0.86, 95% CI, 0.075–0.99) when the 20th percentile of intake (1.7 g/day) was compared with the highest quintile (46.3 g/day).…”
Section: Fiber and Cardiovascular Diseasesupporting
confidence: 90%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.