Central Serous Choroidopathy in Pregnancy

Development of Parafoveal Exudates and Serous Retinal Detachment in a Pregnant Woman with Tuberous Sclerosis

“…Associations between the development of idiopathic central serous choroidopathy and pregnancy, exogenous corticosteroid administration, and hypercortisolism in Cushing's disease have been described, possibly reflecting a corticosteroidinduced alteration in the retinal pigment epithelium or permeability of the choriocapillaries [3]. In addition, a significant increase in blood volume and cardiac output during pregnancy may predispose patients to damage of the choroidal vessels and retinal pigment epithelium [4]. Initially, the retinal edema was severe enough to create a star in the macular area.…”

Development of Parafoveal Exudates and Serous Retinal Detachment in a Pregnant Woman with Tuberous Sclerosis

“…Associations between the development of idiopathic central serous choroidopathy and pregnancy, exogenous corticosteroid administration, and hypercortisolism in Cushing's disease have been described, possibly reflecting a corticosteroidinduced alteration in the retinal pigment epithelium or permeability of the choriocapillaries [3]. In addition, a significant increase in blood volume and cardiac output during pregnancy may predispose patients to damage of the choroidal vessels and retinal pigment epithelium [4]. Initially, the retinal edema was severe enough to create a star in the macular area.…”

Experimental Studies on the Accumulation of Subretinal Fluid

“…Diffuse damage to the RPF, on the other hand, could produce a compromised eye which cannot cope with the fluid entering through a small RPE defect. The concept of diffuse disease is also consistent with the fact that serous detachments can occur in associ ation with systemic diseases such as hyperten sion [17], lupus erythematosus [18], complica tions of pregnancy [19,20], disseminated in travascular coagulation [21] and thrombotic thrombocytopenia [22]. Furthermore, detach ments can be experimentally produced in ani mals by systemic or diffuse ocular treatments such as injections of adrenalin [23,24] or occlu sion of the posterior ciliary arteries [23,26].…”

Viagra-associated serous macular detachment

“…Subretinal leakage due to altered choroidal vascular perfusion and permeability occurs in systemic inflammatory and infectious diseases with fluid extension into the subretinal space [34]. Systemic malignant hypertension, toxemia of pregnancy, and hypercoagulable states may result in choriocapillaris occlusion and choroidal ischemia with subsequent breakdown of the outer bloodocular barrier and serous detachment [1,11]. The integrity of the choroidal vasculature and its impact on subretinal fluid accumulation plays a paramount role in normal retinal adhesion [8].…”

Development of Parafoveal Exudates and Serous Retinal Detachment in a Pregnant Woman with Tuberous Sclerosis

“…Associations between the development of idiopathic central serous choroidopathy and pregnancy, exogenous corticosteroid administration, and hypercortisolism in Cushing's disease have been described, possibly reflecting a corticosteroidinduced alteration in the retinal pigment epithelium or permeability of the choriocapillaries [3]. In addition, a significant increase in blood volume and cardiac output during pregnancy may predispose patients to damage of the choroidal vessels and retinal pigment epithelium [4]. Initially, the retinal edema was severe enough to create a star in the macular area.…”

Experimental Studies on the Accumulation of Subretinal Fluid

“…Diffuse damage to the RPF, on the other hand, could produce a compromised eye which cannot cope with the fluid entering through a small RPE defect. The concept of diffuse disease is also consistent with the fact that serous detachments can occur in associ ation with systemic diseases such as hyperten sion [17], lupus erythematosus [18], complica tions of pregnancy [19,20], disseminated in travascular coagulation [21] and thrombotic thrombocytopenia [22]. Furthermore, detach ments can be experimentally produced in ani mals by systemic or diffuse ocular treatments such as injections of adrenalin [23,24] or occlu sion of the posterior ciliary arteries [23,26].…”

Viagra-associated serous macular detachment

“…Subretinal leakage due to altered choroidal vascular perfusion and permeability occurs in systemic inflammatory and infectious diseases with fluid extension into the subretinal space [34]. Systemic malignant hypertension, toxemia of pregnancy, and hypercoagulable states may result in choriocapillaris occlusion and choroidal ischemia with subsequent breakdown of the outer bloodocular barrier and serous detachment [1,11]. The integrity of the choroidal vasculature and its impact on subretinal fluid accumulation plays a paramount role in normal retinal adhesion [8].…”

Development of Parafoveal Exudates and Serous Retinal Detachment in a Pregnant Woman with Tuberous Sclerosis

“…Associations between the development of idiopathic central serous choroidopathy and pregnancy, exogenous corticosteroid administration, and hypercortisolism in Cushing's disease have been described, possibly reflecting a corticosteroidinduced alteration in the retinal pigment epithelium or permeability of the choriocapillaries [3]. In addition, a significant increase in blood volume and cardiac output during pregnancy may predispose patients to damage of the choroidal vessels and retinal pigment epithelium [4]. Initially, the retinal edema was severe enough to create a star in the macular area.…”

Experimental Studies on the Accumulation of Subretinal Fluid

“…Diffuse damage to the RPF, on the other hand, could produce a compromised eye which cannot cope with the fluid entering through a small RPE defect. The concept of diffuse disease is also consistent with the fact that serous detachments can occur in associ ation with systemic diseases such as hyperten sion [17], lupus erythematosus [18], complica tions of pregnancy [19,20], disseminated in travascular coagulation [21] and thrombotic thrombocytopenia [22]. Furthermore, detach ments can be experimentally produced in ani mals by systemic or diffuse ocular treatments such as injections of adrenalin [23,24] or occlu sion of the posterior ciliary arteries [23,26].…”

Viagra-associated serous macular detachment

“…Subretinal leakage due to altered choroidal vascular perfusion and permeability occurs in systemic inflammatory and infectious diseases with fluid extension into the subretinal space [34]. Systemic malignant hypertension, toxemia of pregnancy, and hypercoagulable states may result in choriocapillaris occlusion and choroidal ischemia with subsequent breakdown of the outer bloodocular barrier and serous detachment [1,11]. The integrity of the choroidal vasculature and its impact on subretinal fluid accumulation plays a paramount role in normal retinal adhesion [8].…”