Central retinal artery occlusion associated with patent foramen ovale: a case report and literature review

Steinberg, Yael; Blace, Nancy; Szlechter, Moshe; Shulman, Eric; Thankenchen, Jincy; Mbekeani, Joyce N.

doi:10.5935/0004-2749.20210073

Cited by 11 publications

(8 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…RAOs including BRAO and CRAO are infrequent in childhood and young adults, occurring even more occasionally in the setting of pregnancy [1]. The RECO study group [2] and the American Academy of Ophthalmology (AAO) emphasized [3] the importance of a systematic Case Reports in Ophthalmology evaluation of young patients with RAO, presenting results of almost 1 out of every 2 patients with acute RAO had an echocardiography with cardiac abnormality and were deemed to be at high risk for cardioembolic diseases. During pregnancy, it is well established the presence of a hypercoagulable state induced by the Virchow triad.…”

Section: Discussionmentioning

confidence: 99%

OCT Angiography Use in Pregnancy: Branch Retinal Artery Occlusion Associated with Patent Foramen Ovale – A Case Report and Multimodal Analysis

Pipolo

Neto²,

Ishida³

et al. 2023

Case Rep Ophthalmol

View full text Add to dashboard Cite

This case report is a multimodal analysis of a pregnant patient with branch retinal artery occlusion (BRAO) associated to patent foramen ovale (PFO). A 28-year-old woman presented at the clinic 20 h after an acute, painless black spot appearance in the inferior temporal visual field of the right eye (OD). At that time, she was 18 weeks pregnant and had no report of complications in her previous pregnancy. Best-corrected visual acuity was 1.0 in both eyes. Color fundus photo, perimetry, and OCT angiography were required. The results clearly showed an embolus in the superior nasal retinal arteriole, associated with a pallor in the distal retina. Patient was referred to a cardiologist and a transcranial Doppler with contrast indicated a right-to-left intracardiac shunt, confirmed by the presence of a PFO at the transesophageal echocardiography. Thrombophilic conditions were excluded. Enoxaparin 1 mg/kg was started and kept until the delivery. Now, a PFO surgical closure is on schedule. This case highlights the noteworthiness of considering PFO as a source of embolism for BRAO in young patients, the capability of OCTA as a dye-free method for use in pregnancy and emphasizes the importance of systemic evaluation in patients with BRAO.

show abstract

Section: Discussionmentioning

confidence: 99%

OCT Angiography Use in Pregnancy: Branch Retinal Artery Occlusion Associated with Patent Foramen Ovale – A Case Report and Multimodal Analysis

Pipolo

Neto²,

Ishida³

et al. 2023

Case Rep Ophthalmol

View full text Add to dashboard Cite

show abstract

“…They also conducted a review of literature and found seven such other cases, in which PFO has been implicated as a causative factor of CRAO. In their review, they cited transesophageal echocardiogram (TEE) as being more sensitive in diagnosing PFO as compared to TTE [ 9 , 10 ]. Our case also reported a similar occurrence of CRAO and PFO.…”

Section: Discussionmentioning

confidence: 99%

Central retinal artery occlusion as a result of symptomatic patent foramen ovale

Tayyab

Aamir

Kirmani

2023

rjo

View full text Add to dashboard Cite

“…In addition to the abnormal vascular tortuosity found in up to 35% of CHD cases,2 other prevalent retinal repercussions include changes in diameters and increased vascular branching.8 In addition to the significant correlations reported between decreased arterial caliber and increased vein caliber with cardiovascular disease, there are reports of retinal vessel capillary disease (ischemia, hemorrhage), thromboembolic events. [29][30][31][32][33][34][35][36][37][38]40 According to the literature, these changes also occur more frequently in individuals with cyanotic CHD. 20 Prematurity and low birth weight also play an important role in increasing vascular tortuosity, regardless of retinopathy of prematurity.19,39 In addition to the presence of retinopathy, strabismus was highly prevalent in patients with congenital heart disease (11.7%) in the present study.…”

Section: Retinal Vascular Changes and Chdmentioning

confidence: 99%

Identifying Eye Changes in Children and Adolescents with Congenital Heart Disease with the Aid of a Smartphone: An Observational Study

Mengue¹,

Pellanda²,

Parodi³

et al. 2023

MRAJ

View full text Add to dashboard Cite

Background: Among congenital diseases, congenital heart disease is one of the most frequent defects, accounting for high morbidity and mortality rates. Coexistence of ocular sequelae, especially in retinal microvascularization, is frequent, and may be a marker of vascular damage and severity of underlying disease. Aims: To identify ocular anatomical repercussions in children with congenital heart diseases; to describe the prevalence of potential markers associated with retinal vessels using a smartphone. Methods: This was a cross-sectional observational study with children diagnosed with congenital heart disease treated at the Instituto de Cardiologia in Porto Alegre-RS from 4 up to (but not over) 18 years old. Results: Of a total of 218 patients assessed, 206 were included in the study. Mean age was 10.19 years +- 3.88. Uncorrected visual acuity poorer than 0.6 in at least one eye was found in 11.65% (24) of all patients. Regarding retinal findings, estimated mean arterial tortuosity was 437.79 μm, and estimated mean venous tortuosity was 336.41 μm. Taking only the cyanotic group, the arterial mean reached 557.29 μm, and the venous mean reached 401.86 (p=.001 and p=.004, respectively). In the multivariate analysis, estimated mean arterial tortuosity of cyanotic patients undergoing clinical treatment was 699.13 μm versus 489.74 μm for those without clinical treatment (p<0.001). Conclusion: Presence of retinal vascular tortuosity, especially in the arterial bed, is associated with cyanotic CHD. Identification of ocular changes, especially through an easily accessible and universal method such as the smartphone, may have diagnostic and prognostic significance.

show abstract

Central retinal artery occlusion associated with patent foramen ovale: a case report and literature review

Cited by 11 publications

References 0 publications

OCT Angiography Use in Pregnancy: Branch Retinal Artery Occlusion Associated with Patent Foramen Ovale – A Case Report and Multimodal Analysis

OCT Angiography Use in Pregnancy: Branch Retinal Artery Occlusion Associated with Patent Foramen Ovale – A Case Report and Multimodal Analysis

Central retinal artery occlusion as a result of symptomatic patent foramen ovale

Identifying Eye Changes in Children and Adolescents with Congenital Heart Disease with the Aid of a Smartphone: An Observational Study

Contact Info

Product

Resources

About