Central Nervous System Magnetic Resonance Imaging Findings in Myotonic Dystrophy

Pattern and significance of white matter abnormalities in myotonic dystrophy type 1: an MRI study

“…The present study confirms and extends to a larger population of DM1 patients previous neuroimaging findings [1,4,7,8,11,14,19,24], ranging from normal findings to large and confluent WMLs with brain atrophy (Figs. 1, 2), and suggests a probable evolution of white matter abnormalities during the disease.…”

Pattern and significance of white matter abnormalities in myotonic dystrophy type 1: an MRI study

“…The present study confirms and extends to a larger population of DM1 patients previous neuroimaging findings [1,4,7,8,11,14,19,24], ranging from normal findings to large and confluent WMLs with brain atrophy (Figs. 1, 2), and suggests a probable evolution of white matter abnormalities during the disease.…”

Myotonic Dystrophy as a Brain Disorder

“…3 Cerebral atrophy and focal white matter lesions have been recognized on magnetic resonance (MR) images of brains of patients with DM since the late 1980s. 6 These data confirm the existence of a structural brain disorder in DM. However, availability of brain autopsy materials in DM is limited, and the MR imaging data are difficult to correlate with the histological findings.…”

Current Progress in CNS Imaging of Myotonic Dystrophy

“…There was an increased incidence of ventriculomegaly in DM1 patients. Furthermore, this study gave first evidence of periventricular hyperintensities in DM1 patients when compared to controls ( 6 ).…”

Pattern and significance of white matter abnormalities in myotonic dystrophy type 1: an MRI study

“…The present study confirms and extends to a larger population of DM1 patients previous neuroimaging findings [1,4,7,8,11,14,19,24], ranging from normal findings to large and confluent WMLs with brain atrophy (Figs. 1, 2), and suggests a probable evolution of white matter abnormalities during the disease.…”

Myotonic Dystrophy as a Brain Disorder

“…3 Cerebral atrophy and focal white matter lesions have been recognized on magnetic resonance (MR) images of brains of patients with DM since the late 1980s. 6 These data confirm the existence of a structural brain disorder in DM. However, availability of brain autopsy materials in DM is limited, and the MR imaging data are difficult to correlate with the histological findings.…”

Current Progress in CNS Imaging of Myotonic Dystrophy

“…There was an increased incidence of ventriculomegaly in DM1 patients. Furthermore, this study gave first evidence of periventricular hyperintensities in DM1 patients when compared to controls ( 6 ).…”

Pattern and significance of white matter abnormalities in myotonic dystrophy type 1: an MRI study

“…The present study confirms and extends to a larger population of DM1 patients previous neuroimaging findings [1,4,7,8,11,14,19,24], ranging from normal findings to large and confluent WMLs with brain atrophy (Figs. 1, 2), and suggests a probable evolution of white matter abnormalities during the disease.…”

Myotonic Dystrophy as a Brain Disorder

“…3 Cerebral atrophy and focal white matter lesions have been recognized on magnetic resonance (MR) images of brains of patients with DM since the late 1980s. 6 These data confirm the existence of a structural brain disorder in DM. However, availability of brain autopsy materials in DM is limited, and the MR imaging data are difficult to correlate with the histological findings.…”

Current Progress in CNS Imaging of Myotonic Dystrophy

“…There was an increased incidence of ventriculomegaly in DM1 patients. Furthermore, this study gave first evidence of periventricular hyperintensities in DM1 patients when compared to controls ( 6 ).…”