2018
DOI: 10.4172/2329-6895.1000393
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Abstract: Background: The neural mechanisms of chronic migraine remain largely unknown but linked to the decreased connectivity to intrinsic brain networks. Objective: To characterize the intranetwork functional connectivity within the Central Executive Network (CEN) and Default Mode Network (DMN) in chronic migraine (CM), with and without medication overuse headache (MOH). Methods: Using functional magnetic resonance imaging, we performed post-hoc analysis of a total of 136 pairs of nodes to node functional connect… Show more

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Cited by 36 publications
(26 citation statements)
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“…Torta et al (28) showed evidence of nucleus accumbens to orbitofrontal functional dysregulation of the reward system that distinguished individual patients with MOH from migraineurs with a 75% accuracy. Two studies by Androulakis and colleagues suggest alterations in frontallimbic networks and less functional connectivity within the left prefrontal cortex and between the right prefrontal cortex and the left anterior thalamus (12,13).…”
Section: Brain Function and The Mesocortical-limbic Circuitmentioning
confidence: 99%
“…Torta et al (28) showed evidence of nucleus accumbens to orbitofrontal functional dysregulation of the reward system that distinguished individual patients with MOH from migraineurs with a 75% accuracy. Two studies by Androulakis and colleagues suggest alterations in frontallimbic networks and less functional connectivity within the left prefrontal cortex and between the right prefrontal cortex and the left anterior thalamus (12,13).…”
Section: Brain Function and The Mesocortical-limbic Circuitmentioning
confidence: 99%
“…9 The painrelated brain regions primarily included the thalamus, insula and anterior cingulate, while other brain regions were likely to be stimulus-specific. 10 In recent years, many studies have valuated the underlying neurophysiological mechanism of brain functional changes in low back pain, 11 trigeminal neuralgia, 12 chronic migraine, 13,14 fibromyalgia, 15 knee osteoarthritis, 16 visceral pain, 17 but literature focused on abnormal pattern of cerebral networks for pain processing in patients with shoulder pain is insufficient. In the brain, the functional interaction effects of pain, cognitive as well as negative affect have been widely reported 18,19 and multiple mechanisms are needed to fully explain the emotional and cognitive brain alternations associated with pain.…”
Section: Introductionmentioning
confidence: 99%
“…Overall, many neuroimaging studies have demonstrated that patients with pain-related symptoms have abnormal neuronal activity and structural function, [11][12][13][14][15][16][17] few have focused on chronic shoulder pain. Therefore, the main objective of our study is to investigate how chronic shoulder pain affects brain function.…”
Section: Introductionmentioning
confidence: 99%
“…There are two main ways of describing alterations in brain networks using this method: to explore within‐ or between‐network FC. Most of the previous studies using seed‐base analysis reported about changes in FC of one or two networks whereas very few studies evaluated complex networks interaction models 3‐5 …”
Section: Introductionmentioning
confidence: 99%