Central Corneal Thickness and Glaucoma in Aphakic and Pseudophakic Children

Simon, John W.; O’Malley, Martin R.; Gandham, Sai B.; Ghaiy, Rajat; Zobal-Ratner, Jitka; Simmons, Steven T.

doi:10.1016/j.jaapos.2005.02.014

Cited by 43 publications

(50 citation statements)

References 12 publications

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“…A comparative study of central corneal thickness in aphakic and pseudophakic children compared with age matched normal controls, demonstrated that the mean corneal thickness was 626 and 556 m, respectively. 46 Similar findings were reported by Simon et al 47 This increased corneal thickness is likely to falsely elevate the measured intraocular pressure. Thus, careful consideration of optic nerve and visual field changes (where possible) are essential to diagnostic accuracy.…”

Section: Complicationssupporting

confidence: 76%

Advances in the management of congenital and infantile cataract

Lloyd

Ashworth

Biswas

et al. 2007

Eye

113

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Section: Complicationssupporting

confidence: 76%

Advances in the management of congenital and infantile cataract

Lloyd

Ashworth

Biswas

et al. 2007

Eye

113

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“…12 Surgical trauma to the cornea during the first months of life might impair these regulatory mechanisms, interrupting normal corneal development. Simon et al 10 found normal CCT values in the phakic fellow eyes of patients with unilateral aphakia. Based on our data and previous results, we postulate that surgical trauma is an important factor for increasing CCT.…”

Section: Discussionmentioning

confidence: 96%

“…This finding supports an earlier report that found a significantly increased average CCT of 660 mm in a group of 28 aphakic patients. 10 In that report, the CCT was compared with that of phakic eyes within patients, instead of with the eyes of healthy subjects. As only five patients had unilateral aphakia in our study, we could not compare aphakic and phakic eyes within patients.…”

Section: Discussionmentioning

confidence: 99%

Glaucoma and increased central corneal thickness in aphakic and pseudophakic patients after congenital cataract surgery

Şimşek¹

2006

British Journal of Ophthalmology

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Aim: To compare the mean central corneal thickness (CCT) among aphakic and pseudophakic patients following congenital cataract surgery with age matched controls. Methods: This study included 43 eyes of 43 aphakic and pseudophakic patients following congenital cataract surgery. 44 healthy, age and sex matched volunteers were recruited for comparison with the patients. After a complete eye examination, corneal thickness and intraocular pressure were measured. Results: In the study group, 33 eyes were aphakic, and the remaining 10 eyes were pseudophakic. The median CCT was 556.0 mm (range 490-640 mm) in the control group and 626 mm (range 523-870 mm) in the study group (p,0.05). There was a significant difference in CCT between aphakic and pseudophakic eyes in which an intraocular lens (IOL) had been implanted at the time of congenital cataract surgery (p = 0.011). The same difference was not observed between aphakic and pseudophakic eyes in which an IOL had been implanted secondarily (p = 0.835). The median age of the patients at the time of lensectomy was 24 months (range 1 week to 120 months). There was a negative correlation between the age at lensectomy and CCT (r = 20.485, p = 0.001). Conclusion: Aphakic and pseudophakic patients have significantly thicker corneas than age matched controls. This difference can have an important effect on interpreting intraocular pressures in these patients. It is also important to assess the effects of early surgery for congenital cataracts, as well as those of primary and secondary IOL implantation, on CCT.

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“…Sabe-se que olhos afácicos de crianças possuem uma espessura central da córnea maior que olhos fácicos (8,9) . Kelly et al recentemente relataram um aumento de 45% de crianças afácicas (maior ECC) que desenvolveram glaucoma (14) .…”

Section: Discussionunclassified

“…A córnea da criança prematura e recém-nascida é mais espessa que a córnea do adulto; após 48 horas do nascimento, a córnea já está menos espessa e próximo aos 3 anos atinge o valor definitivo. (7) Crianças com história de catarata congênita que são afácicas ou pseudofácicas possuem ECC maior que crianças com cristalino transparente (8,9) , mas é desconhecido se o aumento da espessura central da córnea ocorre antes da cirurgia ou se desenvolve após a mesma. O glaucoma é uma consequência comum em cirurgia de catarata congênita (10) , e uma espessura corneana fora dos limites normais talvez seja um fator importante no diagnóstico e conduta de crianças pseudofácicas e afácicas com glaucoma, pois o efeito da ECC pode falsear a medida da pressão intraocular (PIO).…”

Section: Introductionunclassified

Espessura central da córnea: catarata congênita, pseudofacia e afacia

Santos

Siqueira

Salomão

et al. 2010

Rev. bras.oftalmol.

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RESUMOObjetivo: Comparação da espessura central da córnea entre crianças com cristalino transparente (controle), catarata, pseudofácicas e afácicas. Estudo prospectivo, observacional. Métodos: Noventa e quatro olhos de 47 crianças foram submetidos à medida da espessura central corneana (ECC) e comparou-se o grupo controle (cristalino transparente) aos pacientes que apresentavam catarata, afacia ou pseudofacia. Pacientes com Síndrome de Down, aniridia, Síndrome de Marfan, glaucoma, anormalidades do segmento anterior ou pressão intraocular maior que 30 mmHg foram excluídos do estudo. Resultados: Dos 94 olhos estudados, 52 faziam parte do grupo controle com ECC média 533,6 µm. No grupo com catarata (n=27) a ECC média foi de 532,3 µm, enquanto no grupo de afácicos (n=8) e pseudofácicos (n=12) de 585,63 µ e 585,7 µ, respectivamente. Conclusão: A espessura central da córnea é semelhante em olhos com catarata congênita e olhos fácicos, sendo mais espessa após a cirurgia de catarata com ou sem implante de lente intraocular.

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Central Corneal Thickness and Glaucoma in Aphakic and Pseudophakic Children

Cited by 43 publications

References 12 publications

Advances in the management of congenital and infantile cataract

Advances in the management of congenital and infantile cataract

Glaucoma and increased central corneal thickness in aphakic and pseudophakic patients after congenital cataract surgery

Espessura central da córnea: catarata congênita, pseudofacia e afacia

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