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Cited by 25 publications
(9 citation statements)
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References 21 publications
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“…This is in line with the findings reported by other authors (Mauney et al, 2004). Stanford et al (1995) observed a dose-dependent suppression of bone specific mRNA levels in calvarial osteoblasts. Our protocol was optimized according to our previous experience and the reported protocols for osteogenic differentiation under the influence of mechanical stimulation (Jagodzinski et al, 2004Mauney et al, 2004).…”
Section: Article In Presssupporting
confidence: 94%
“…This is in line with the findings reported by other authors (Mauney et al, 2004). Stanford et al (1995) observed a dose-dependent suppression of bone specific mRNA levels in calvarial osteoblasts. Our protocol was optimized according to our previous experience and the reported protocols for osteogenic differentiation under the influence of mechanical stimulation (Jagodzinski et al, 2004Mauney et al, 2004).…”
Section: Article In Presssupporting
confidence: 94%
“…These observations suggest that mechanical stress induces an inflammatory response in the cells of the PDL; however, the exact nature of this response still needs to be analyzed. Several studies performed on rat calvarial cell cultures grown in vitro have shown that mechanical stress induced increased synthesis of PGE2 (Binderman et al, 1988;Rawlinson et al, 1995;Klein-Nulend et al, 1996;Zhuang et al, 1996), decreased alkaline phosphatase activity, and reduced the synthesis of osteocalcin (Roelofsen et al, 1995;Stanford et al, 1995;Mikuni-Takagaki et al, 1996), while not affecting collagen synthesis (Hillsley and Frangos, 1997).…”
Section: Introductionmentioning
confidence: 97%
“…The effects of mechanical load/unloading on bony tissue were investigated in different animal, cell and organ culture approaches. Mechanical loading consisting of tension force (14), stretching (15), intermittent hydrostatic compression (16), micro‐ (17, 18), and hypergravity (19) have all been described using in vivo and in vitro systems (18, 20, 21). Recently, Ziros and co‐workers (22) showed an increase in the RUNX2 expression level after 30 min of tension type of loading in a setting using periodontal‐ligament fibroblasts.…”
Section: Introductionmentioning
confidence: 99%