Cellular and molecular osmoregulatory responses to cadmium exposure in Gammarus fossarum (Crustacea, Amphipoda)

Issartel, Julien; Boulo, Viviane; Wallon, Sophie; Geffard, Olivier; Charmantier, Guy

doi:10.1016/j.chemosphere.2010.07.063

Cited by 39 publications

(31 citation statements)

References 38 publications

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“…water-borne pollutants, pathological agents or environmental stressors) usually leads to disturbance in Na + and Cl − regulation and/or in osmoregulatory capacity [17], [29], [65]. The effects of AsV on iono−/osmo-regulation are little documented while they have been well studied for Cd, even if reported patterns are contrasted.…”

Section: Discussionmentioning

confidence: 99%

Behavioural and Physiological Responses of Gammarus pulex Exposed to Cadmium and Arsenate at Three Temperatures: Individual and Combined Effects

et al. 2012

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This study aimed at investigating both the individual and combined effects of cadmium (Cd) and arsenate (AsV) on the physiology and behaviour of the Crustacean Gammarus pulex at three temperatures (5, 10 and15°C). G. pulex was exposed during 96 h to (i) two [Cd] alone, (ii) two [AsV] alone, and (iii) four combinations of [Cd] and [AsV] to obtain a complete factorial plane. After exposure, survival, [AsV] or [Cd] in body tissues, behavioural (ventilatory and locomotor activities) and physiological responses (iono-regulation of [Na+] and [Cl−] in haemolymph) were examined. The interactive effects (antagonistic, additive or synergistic) of binary mixtures were evaluated for each tested temperature using a predictive model for the theoretically expected interactive effect of chemicals. In single metal exposure, both the internal metal concentration in body tissues and the mortality rate increased along metallic gradient concentration. Cd alone significantly impaired both [Na+] and [Cl−] while AsV alone had a weak impact only on [Cl−]. The behavioural responses of G. pulex declined with increasing metal concentration suggesting a reallocation of energy from behavioural responses to maintenance functions. The interaction between AsV and Cd was considered as ‘additive’ for all the tested binary mixtures and temperatures (except for the lowest combination at 10°C considered as “antagonistic”). In binary mixtures, the decrease in both ventilatory and locomotor activities and the decline in haemolymphatic [Cl−] were amplified when respectively compared to those observed with the same concentrations of AsV or Cd alone. However, the presence of AsV decreased the haemolymphatic [Na+] loss when G. pulex was exposed to the lowest Cd concentration. Finally, the observed physiological and behavioural effects (except ventilation) in G. pulex exposed to AsV and/or Cd were exacerbated under the highest temperature. The discussion encompasses both the toxicity mechanisms of these metals and their interaction with rising temperature.

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Section: Discussionmentioning

confidence: 99%

Behavioural and Physiological Responses of Gammarus pulex Exposed to Cadmium and Arsenate at Three Temperatures: Individual and Combined Effects

et al. 2012

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“…Gills of G. fossarum are one of the first organs that are directly exposed to contaminants in the water (Felten et al, 2008b;Henry and Wheatly, 1992;Issartel et al, 2010;Lignot et al, 2000;Pequeux, 1995) and were therefore selected for AgNPs uptake evaluation.…”

Section: Particle Uptake In Gills Of G Fossarummentioning

confidence: 99%

Gammarus fossarum (Crustacea, Amphipoda) as a model organism to study the effects of silver nanoparticles

Mehennaoui

Georgantzopoulou

Felten

et al. 2016

Science of The Total Environment

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“…The Na + /K + -ATPase α-subunit mRNA was elevated during the first three days of exposure to cadmium but afterwards was down-regulated to the control value (Issartel et al, 2010). In the gills of the blue crab Callinectes sapidus acclimated to 2 ppt seawater, low copper concentration inhibited expression of mRNA genes encoding the Na + /K + -ATPase.…”

Section: Branchial Transport and Bioaccumulation Of Toxic Metalsmentioning

confidence: 99%

“…Sublethal and chronic exposures of toxic metals induce numerous malformations and ultrastructural changes in the crustacean gill epithelium (Nonnotte et al, 1993; Victor, 1994; Lawson et al, 1995; Rtal et al, 1996; Powert et al, 1998; Hebel et al, 1999; Soegianto et al, 1999; Li et al, 2009; Issartel et al, 2010). Common malformations are characterized by thickened gill cells with reduced haemolymphatic space, cellular hyperplasia, and necrosis.…”

Section: Branchial Transport and Bioaccumulation Of Toxic Metalsmentioning

confidence: 99%

Multiple functions of the crustacean gill: osmotic/ionic regulation, acid-base balance, ammonia excretion, and bioaccumulation of toxic metals

Henry¹,

Lucu²,

Onken³

et al. 2012

Front. Physio.

365

286

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The crustacean gill is a multi-functional organ, and it is the site of a number of physiological processes, including ion transport, which is the basis for hemolymph osmoregulation; acid-base balance; and ammonia excretion. The gill is also the site by which many toxic metals are taken up by aquatic crustaceans, and thus it plays an important role in the toxicology of these species. This review provides a comprehensive overview of the ecology, physiology, biochemistry, and molecular biology of the mechanisms of osmotic and ionic regulation performed by the gill. The current concepts of the mechanisms of ion transport, the structural, biochemical, and molecular bases of systemic physiology, and the history of their development are discussed. The relationship between branchial ion transport and hemolymph acid-base regulation is also treated. In addition, the mechanisms of ammonia transport and excretion across the gill are discussed. And finally, the toxicology of heavy metal accumulation via the gill is reviewed in detail.

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Cellular and molecular osmoregulatory responses to cadmium exposure in Gammarus fossarum (Crustacea, Amphipoda)

Cited by 39 publications

References 38 publications

Behavioural and Physiological Responses of Gammarus pulex Exposed to Cadmium and Arsenate at Three Temperatures: Individual and Combined Effects

Behavioural and Physiological Responses of Gammarus pulex Exposed to Cadmium and Arsenate at Three Temperatures: Individual and Combined Effects

Gammarus fossarum (Crustacea, Amphipoda) as a model organism to study the effects of silver nanoparticles

Multiple functions of the crustacean gill: osmotic/ionic regulation, acid-base balance, ammonia excretion, and bioaccumulation of toxic metals

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