Cell life on the surface of lens implants

Abstract

A simple technique called lens implant cytology is used to demonstrate cellular membranes on three plastic intraocular lenses removed at about 1, 2 and 3 years after implantation. The pattern of the reactive process somewhat resembles a special foreign body reaction. The cells living on the lens surface have successfully formed a separating membrane between implants and the remainder of the eye in all three cases. Zusammenfassung. Eine einfache Methode, Linsenimplant Zytologie genannt, wurde benutzt, um zellige Membranen auf drei Plastiklinsen darzustellen, die 1, 2 und 3 Jahre nach Einpflanzung entfernt wurden. Der beobachtete reaktive Prozeg ist einer besonderen Fremdk6rperreaktion fihnlich. Die Zellen auf der LinsenoberflS.che haben in allen drei Ffillen mit Erfolg eine trennende Schicht zwischen Plastiklinse und innerem Auge geschaffen.

Abdominal implantation of intraocular lenses resulting in the formation of reactive membranes

“…Study of the giant cells allowed for the recognition of different stages of their formation, and it could be concluded that they develop by protoplasmic fusion of macrophages. The arrangement of the nuclei in the form of perfect rings around the protoplasmatic centers of the giant cells has been observed before in the giant cells on the surface of implants removed from human eyes [1,8]. However, giant cells on human lens implants may also have the irregular arrangement of their nuclei all through the protoplasm that is typical for foreignbody giant cells ~ [2,6].…”

Abdominal implantation of intraocular lenses resulting in the formation of reactive membranes

“…Study of the giant cells allowed for the recognition of different stages of their formation, and it could be concluded that they develop by protoplasmic fusion of macrophages. The arrangement of the nuclei in the form of perfect rings around the protoplasmatic centers of the giant cells has been observed before in the giant cells on the surface of implants removed from human eyes [1,8]. However, giant cells on human lens implants may also have the irregular arrangement of their nuclei all through the protoplasm that is typical for foreignbody giant cells ~ [2,6].…”

Reactive membrane on a lens implant: three months after implantation

“…Three months after surgery the film-like acellular part of the membrane covering the implant was of a looser and more eosinophilic composition than membranes that have been studied on implants removed years after surgery [1][2][3][4][5]. Study of the cells in the membrane covering the present implant revealed a much more important fact: the different cell types that have already been observed on other implants were all present, but they all appeared to be less differentiated and clearly interrelated.…”

In vivo Observation of Surface Precipitates of 200 Consecutive Hydrogel Intraocular Lenses

“…In 1 case, they formed membranes as it is already described for some polymethy lmetha- 14 Amon/Menapacc In vivo Observation of Surface Precipitates of 200 Consecutive Hydrogel Intraocular Lenses crylate (PMMA) cases [9] (fig. 3).…”

Abdominal implantation of intraocular lenses resulting in the formation of reactive membranes

“…Study of the giant cells allowed for the recognition of different stages of their formation, and it could be concluded that they develop by protoplasmic fusion of macrophages. The arrangement of the nuclei in the form of perfect rings around the protoplasmatic centers of the giant cells has been observed before in the giant cells on the surface of implants removed from human eyes [1,8]. However, giant cells on human lens implants may also have the irregular arrangement of their nuclei all through the protoplasm that is typical for foreignbody giant cells ~ [2,6].…”

Reactive membrane on a lens implant: three months after implantation

“…Three months after surgery the film-like acellular part of the membrane covering the implant was of a looser and more eosinophilic composition than membranes that have been studied on implants removed years after surgery [1][2][3][4][5]. Study of the cells in the membrane covering the present implant revealed a much more important fact: the different cell types that have already been observed on other implants were all present, but they all appeared to be less differentiated and clearly interrelated.…”

In vivo Observation of Surface Precipitates of 200 Consecutive Hydrogel Intraocular Lenses

“…In 1 case, they formed membranes as it is already described for some polymethy lmetha- 14 Amon/Menapacc In vivo Observation of Surface Precipitates of 200 Consecutive Hydrogel Intraocular Lenses crylate (PMMA) cases [9] (fig. 3).…”

Abdominal implantation of intraocular lenses resulting in the formation of reactive membranes

“…Study of the giant cells allowed for the recognition of different stages of their formation, and it could be concluded that they develop by protoplasmic fusion of macrophages. The arrangement of the nuclei in the form of perfect rings around the protoplasmatic centers of the giant cells has been observed before in the giant cells on the surface of implants removed from human eyes [1,8]. However, giant cells on human lens implants may also have the irregular arrangement of their nuclei all through the protoplasm that is typical for foreignbody giant cells ~ [2,6].…”

Reactive membrane on a lens implant: three months after implantation

“…Three months after surgery the film-like acellular part of the membrane covering the implant was of a looser and more eosinophilic composition than membranes that have been studied on implants removed years after surgery [1][2][3][4][5]. Study of the cells in the membrane covering the present implant revealed a much more important fact: the different cell types that have already been observed on other implants were all present, but they all appeared to be less differentiated and clearly interrelated.…”

In vivo Observation of Surface Precipitates of 200 Consecutive Hydrogel Intraocular Lenses

“…In 1 case, they formed membranes as it is already described for some polymethy lmetha- 14 Amon/Menapacc In vivo Observation of Surface Precipitates of 200 Consecutive Hydrogel Intraocular Lenses crylate (PMMA) cases [9] (fig. 3).…”