Essentials of Apoptosis 2009
DOI: 10.1007/978-1-60327-381-7_16
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Cell Death in Drosophila

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“…Ribosome construction is essential to maintain cellular homeostasis and is also the single most expensive metabolic process for a cell (Raska et al, 2004). A dividing mammalian cell requires 10 million ribosomes (Purves, 2000), and a rapidly growing bacterial cell requires as many as 20,000 ribosomes (Berg et al, 2006). Therefore, the downregulation of ribosomal protein genes results in the corresponding reduction of ribosome proteins, thus decreasing the quantity of ribosomes in a cell (Korostelev et al, 2006).…”
Section: Discussionmentioning
confidence: 99%
“…Ribosome construction is essential to maintain cellular homeostasis and is also the single most expensive metabolic process for a cell (Raska et al, 2004). A dividing mammalian cell requires 10 million ribosomes (Purves, 2000), and a rapidly growing bacterial cell requires as many as 20,000 ribosomes (Berg et al, 2006). Therefore, the downregulation of ribosomal protein genes results in the corresponding reduction of ribosome proteins, thus decreasing the quantity of ribosomes in a cell (Korostelev et al, 2006).…”
Section: Discussionmentioning
confidence: 99%