2012
DOI: 10.1590/s0004-28032012000300007
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Abstract: -Context -The first degree relatives of celiac patients represent a high risk group for the development of this disorder, so their screening may be crucial in the prevention of long-term complications. Objective -In order to determine the prevalence of celiac disease in a group of first degree relatives of children with proven gluten intolerance, we conducted a prospective study that consisted in the screening of celiac disease, using a capillary immunoassay rapid test that allows a qualitative detection of Ig… Show more

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Cited by 16 publications
(14 citation statements)
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“…In the recent studies the prevalence among first-degree relatives varied between 2.6% to 9.5%, a range that can be consequence of methodological differences used in these studies and the genetic background of the distinct population valued (1,2,5,14,15) . Interesting to notice that our results were similar to those from a recent study conducted in another Portuguese region (Porto) by Andreia Oliveira et al (12) that revealed a prevalence of 2.6% among 268 first degree relatives. A lower genetic variability typical in island inhabitants may be responsible for the slight higher prevalence found in our study.…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…In the recent studies the prevalence among first-degree relatives varied between 2.6% to 9.5%, a range that can be consequence of methodological differences used in these studies and the genetic background of the distinct population valued (1,2,5,14,15) . Interesting to notice that our results were similar to those from a recent study conducted in another Portuguese region (Porto) by Andreia Oliveira et al (12) that revealed a prevalence of 2.6% among 268 first degree relatives. A lower genetic variability typical in island inhabitants may be responsible for the slight higher prevalence found in our study.…”
Section: Discussionsupporting
confidence: 92%
“…Previous studies regarding screening of first degree relatives have shown prevalence of CD in the range of 2.8%-10% (1,3,5,12,15) . Madeira is an island of Portugal with 267,785 inhabitants, 53,988 under the age of 18 years.…”
Section: Introductionmentioning
confidence: 99%
“…The results partially represented in Table 3 and found in meta-analyses [69, 70] of high CD prevalence in children with Down syndrome (more than 5%) and autoimmune thyroid disorders (about 6%) should motivate screening for CD in these cohorts. CD is also common in patients who have a first- and second-degree kinship with persons with CD, at 10 and 2.6%, respectively [71-73]. Meanwhile, progress in the understanding of CD pathogenesis leads to discovery of new CD-associated symptoms and syndromes, facilitating the diagnosis of CD.…”
Section: Screening Strategies In Paediatric Populationsmentioning
confidence: 99%
“…Popp et al (13) have detected positivity at the rate of 8% with Biocard test in first-degree relatives of CD patients. Oliveira et al (14) detected Biocard test positivity at the rate of 4.5% in 268 first-degree relatives of children with CD, and diagnosed CD with histology at the rate of 2.6%. Alarm et al (17) have made a screening with a rapid test in Libyan Children, and have found positivity in 50 out of 2920 (1.7%).…”
Section: Resultsmentioning
confidence: 99%