1995
DOI: 10.1520/jfs13836j
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: The performance of the Microgenics CEDIA® DAU assays for screening amphetamines, barbiturates, benzodiazepines, cocaine, opiates, phencylidine (PC), and tetrahydrocannabinol (THC) was evaluated on the Boehringer Mannheim/Hitachi 717 in urine. Limits of detection ranged from 0.6 ng/mL for PCP, to 34.1 ng/mL for benzodiazepines. The average within run and total precision for these assays ranged from 1.3 to 7.3% for controls at cutoff concentrations, and control values at −25% and +25% of cutoffs. The rate separa… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
21
0
4

Year Published

2000
2000
2018
2018

Publication Types

Select...
4
4

Relationship

0
8

Authors

Journals

citations
Cited by 41 publications
(25 citation statements)
references
References 5 publications
0
21
0
4
Order By: Relevance
“…Bleach has demonstrated falsenegative results across several different immunoassay techniques and is effective at masking the presence of various drugs during GC/MS testing (Baiker, Serrano, & Lindner, 1994;Cody & Schwarzhoff, 1989;Mikkelsen & Ash, 1988;Peace & Tarnai, 2002;Schwarzhoff & Cody, 1993;Wu et al, 1995). A low concentration of hypochlorite (8-64 Al/ml of urine) interfered with GC/MS, radioimmunoassay (RIA), and the fluorescence polarization immunoassay (FPIA) when screening for THC (Baiker et al, 1994).…”
Section: Bleachmentioning
confidence: 99%
See 2 more Smart Citations
“…Bleach has demonstrated falsenegative results across several different immunoassay techniques and is effective at masking the presence of various drugs during GC/MS testing (Baiker, Serrano, & Lindner, 1994;Cody & Schwarzhoff, 1989;Mikkelsen & Ash, 1988;Peace & Tarnai, 2002;Schwarzhoff & Cody, 1993;Wu et al, 1995). A low concentration of hypochlorite (8-64 Al/ml of urine) interfered with GC/MS, radioimmunoassay (RIA), and the fluorescence polarization immunoassay (FPIA) when screening for THC (Baiker et al, 1994).…”
Section: Bleachmentioning
confidence: 99%
“…Compared with other assays, the CEDIA appears to be most affected by bleach adulteration. Wu et al (1995) reported that bleach interfered with screening for drugs other than THC, including amphetamine, barbiturates, benzodiazepines, cocaine, opiates, and PCP in the CEDIA, with concentrations as low as 1% (Wu et al, 1995). Bleach is also extremely effective in adulterating urine screens positive for barbiturates, benzodiazepines, cocaine, and opiates in the EIA (Mikkelsen & Ash, 1988).…”
Section: Bleachmentioning
confidence: 99%
See 1 more Smart Citation
“…8 Although laboratory immunoassays vary according to their type and cut-off values, as an example for comparison the commonly used cloned enzyme donor immunoassay (CEDIA) system carries an average sensitivity of 98.9% (95% CI 98-100). 12 It has been suggested that on-site kits are best suited for testing small numbers of samples, and are probably unsuitable for widespread routine use. 10 Given the frequent use of these kits, it is original papers…”
Section: Indications For Usementioning
confidence: 99%
“…As a result, goldenseal is taken orally with the idea that a person using the herbal supplement can pass a routine urine drug test. There has been conflicting research published stating if ingested goldenseal or other detoxifying agents on the market, actually do mask the illegal drugs that should appear in a routine urine drug test [1,2]. Dietary supplements are also found to contain goldenseal, which may stand alone or be paired with Echinacea [3].…”
Section: Introductionmentioning
confidence: 99%