CDKN2B-AS1 gene rs4977574 polymorphism in the severity of coronary artery disease in the Kazakh population
Askhat Myngbay,
Serik Alibekov
Abstract:Coronary artery disease (CAD) is one of the leading diseases contributing to mortality. Although it has a hereditary nature, its genetic etiology remains unclear. Recently, many studies showed genetic risk factors using genome-wide association studies, and gene variant association with CAD. Despite the recent breakthroughs on various single nucleotide polymorphisms (SNP) linked to CAD, encompassing genes affecting metabolic disorders, influencing endothelial and smooth muscle dysfunctions, leading to plaque fo… Show more
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