Abstract:CDK9 is an important cell-cycle control enzyme essential in transcription, elongation, and
mRNA maturation. Overexpression of CDK9 has been reported in several diseases, including acute
lymphoblastic leukemia, chronic lymphocytic leukemia, and malignant melanoma. Recent research
revealed that CDK9-inhibitors have a major impact on the induction of apoptosis in hepatocellular
carcinoma (HCC) cell lines. Despite surprisingly promising results in in vitro and in vivo research,
no CDK9 related therapy is currently… Show more
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