Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2016
2016
2017
2017

Publication Types

Select...
2

Relationship

1
1

Authors

Journals

citations
Cited by 3 publications
(2 citation statements)
references
References 8 publications
(9 reference statements)
0
2
0
Order By: Relevance
“…For instance, CD47 is an integrin-associated protein, known as an universal molecular "market of self," involved in the inhibition of phagocytosis, antiinflammation processes, apoptosis, proliferation, adhesion, and migration. [158] This transmembrane protein binds to signal regulatory protein alpha expressed by macrophages and myeloid cells, activating a sign known as "do not eat me" and suppressing the phagocytic processes. [159] As a consequence, surface modification of PLGA nanoparticles with CD47 market, considered as a "stealth or inert artificial structure," is indeed one of the most promising strategies to escape phagocyte uptake and consequently, early PLGA-based DDSs clearance.…”
Section: Functionalized Poly(lactic-co-glycolic) Acid-based Drug Delimentioning
confidence: 99%
“…For instance, CD47 is an integrin-associated protein, known as an universal molecular "market of self," involved in the inhibition of phagocytosis, antiinflammation processes, apoptosis, proliferation, adhesion, and migration. [158] This transmembrane protein binds to signal regulatory protein alpha expressed by macrophages and myeloid cells, activating a sign known as "do not eat me" and suppressing the phagocytic processes. [159] As a consequence, surface modification of PLGA nanoparticles with CD47 market, considered as a "stealth or inert artificial structure," is indeed one of the most promising strategies to escape phagocyte uptake and consequently, early PLGA-based DDSs clearance.…”
Section: Functionalized Poly(lactic-co-glycolic) Acid-based Drug Delimentioning
confidence: 99%
“…Furthermore, antibodies and antibody like complexes have an extremely short in vivo half-life [ 18 20 ], whereas 10-200nm particles demonstrate prolonged blood circulation times [ 21 24 ]. Additionally, particles can be co-functionalized with molecules such as CD47 to further enhance in vivo performance [ 25 27 ]. Moreover, antibodies are known to diffuse rapidly into the surrounding tissue impacting the overall efficacy [ 28 ], however nanoparticles have been described more stably associated with targeted tissues [ 29 ].…”
Section: Discussionmentioning
confidence: 99%