Search citation statements
Paper Sections
Select...
1
1
Citation Types
0
2
0
Year Published
2016
2017
Publication Types
Select...
2
Relationship
1
1
Authors
Journals
Cited by 3 publications
(2 citation statements)
References 8 publications
(9 reference statements)
0
2
0
“…For instance, CD47 is an integrin-associated protein, known as an universal molecular "market of self," involved in the inhibition of phagocytosis, antiinflammation processes, apoptosis, proliferation, adhesion, and migration. [158] This transmembrane protein binds to signal regulatory protein alpha expressed by macrophages and myeloid cells, activating a sign known as "do not eat me" and suppressing the phagocytic processes. [159] As a consequence, surface modification of PLGA nanoparticles with CD47 market, considered as a "stealth or inert artificial structure," is indeed one of the most promising strategies to escape phagocyte uptake and consequently, early PLGA-based DDSs clearance.…”
Section: Functionalized Poly(lactic-co-glycolic) Acid-based Drug Delimentioning
confidence: 99%
“…For instance, CD47 is an integrin-associated protein, known as an universal molecular "market of self," involved in the inhibition of phagocytosis, antiinflammation processes, apoptosis, proliferation, adhesion, and migration. [158] This transmembrane protein binds to signal regulatory protein alpha expressed by macrophages and myeloid cells, activating a sign known as "do not eat me" and suppressing the phagocytic processes. [159] As a consequence, surface modification of PLGA nanoparticles with CD47 market, considered as a "stealth or inert artificial structure," is indeed one of the most promising strategies to escape phagocyte uptake and consequently, early PLGA-based DDSs clearance.…”
Section: Functionalized Poly(lactic-co-glycolic) Acid-based Drug Delimentioning
confidence: 99%
“…Furthermore, antibodies and antibody like complexes have an extremely short in vivo half-life [ 18 – 20 ], whereas 10-200nm particles demonstrate prolonged blood circulation times [ 21 – 24 ]. Additionally, particles can be co-functionalized with molecules such as CD47 to further enhance in vivo performance [ 25 – 27 ]. Moreover, antibodies are known to diffuse rapidly into the surrounding tissue impacting the overall efficacy [ 28 ], however nanoparticles have been described more stably associated with targeted tissues [ 29 ].…”
Section: Discussionmentioning
confidence: 99%
scite is a Brooklyn-based startup that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.