2002
DOI: 10.1001/archderm.138.8.1027
|View full text |Cite
|
Sign up to set email alerts
|

CC and CXC Chemokines Are Differentially Expressed in Erythema Multiforme In Vivo

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

1
21
4

Year Published

2003
2003
2024
2024

Publication Types

Select...
4
4

Relationship

0
8

Authors

Journals

citations
Cited by 20 publications
(27 citation statements)
references
References 36 publications
1
21
4
Order By: Relevance
“…Indeed, this chemokine was demonstrated to induce the migration into the skin not only of Th2 but also Th1 cells, which represent the predominant immune mechanism in these patients [29]; moreover, both keratinocytes and mononuclear cells in EM skin were demonstrated to produce and release RANTES [30]. …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Indeed, this chemokine was demonstrated to induce the migration into the skin not only of Th2 but also Th1 cells, which represent the predominant immune mechanism in these patients [29]; moreover, both keratinocytes and mononuclear cells in EM skin were demonstrated to produce and release RANTES [30]. …”
Section: Discussionmentioning
confidence: 99%
“…Spandau et al [30], analyzing messenger RNA expression and protein immunoreactivity patterns, found macrophage IFN-γ inducible gene, IFN-γ inducible protein 10, monocyte chemoattractant protein 1 and RANTES expressed by both basal keratinocytes and mononuclear inflammatory cells in EM. Other authors suggested that the interactions between the cutaneous T-cell-attracting chemokine and the chemokine receptor CCR10 play a role in SJS/TEN patients [31].…”
Section: Introductionmentioning
confidence: 99%
“…IFN-γ stimulates keratinocytes to express various genes, including inflammatory cytokines and chemokines [42,43,44,45], which are also expressed in HAEM lesions [46]. The finding that IFN-γ can also induce/activate SP1 and its target genes supports our previous conclusion that the inflammatory response characteristic of HAEM is multifactorial and includes factors, such as IFN-γ, that are produced by activated virus-specific T cells which infiltrate the HAEM skin in response to Pol expression [6].…”
Section: Discussionmentioning
confidence: 99%
“…In skin tissues, inflammation is likely to be caused by bacterial endotoxin, the wound healing process, various chemokines, and proinflammatory cytokines [11,[21][22][23][24]. As MAPK and PI3K are involved in early intracellular signaling, it is likely that the inhibition of MAPK and PI3K blocks early signaling involved in IFN-g-mediated skin inflammation.…”
Section: Discussionmentioning
confidence: 99%