2021
DOI: 10.1039/d0fd00062k
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Caveolin-1 (cav-1) is a multi-domain membrane protein that is a key player in cell signaling, endocytosis and mechanoprotection. It is the principle component of cholesterol-rich caveolar domains and has been...

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

1
10
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
5
1

Relationship

1
5

Authors

Journals

citations
Cited by 9 publications
(11 citation statements)
references
References 62 publications
1
10
0
Order By: Relevance
“…For example, it has been suggested that Caveolin-1 can induce membrane curvature through cholesterol recruitment, and that such caveolar complexes have central roles in cell signalling. 37 As reported in other works, 1,11 enrichment of specific lipid types around certain surfaces was detected in our simulations. One of the most evident observations was a high probability density of cholesterol around AQP1 and KcsA (Fig.…”
Section: Discussionsupporting
confidence: 89%
See 1 more Smart Citation
“…For example, it has been suggested that Caveolin-1 can induce membrane curvature through cholesterol recruitment, and that such caveolar complexes have central roles in cell signalling. 37 As reported in other works, 1,11 enrichment of specific lipid types around certain surfaces was detected in our simulations. One of the most evident observations was a high probability density of cholesterol around AQP1 and KcsA (Fig.…”
Section: Discussionsupporting
confidence: 89%
“…For example, it has been suggested that Caveolin-1 can induce membrane curvature through cholesterol recruitment, and that such caveolar complexes have central roles in cell signalling. 37…”
Section: Discussionmentioning
confidence: 99%
“…In addition to the actin‐binding proteins, a detailed comparison with other PIP 2 binding proteins will help identify common PIP lipid binding mechanisms. The interplay between membrane curvature and lipid composition has been reported for several proteins, such as the BAR proteins, [48,49] synaptotagmins, [50–54] alpha‐synuclein [55–58] and caveolin [59] . The importance of PIP 2 in synaptotagmin function has been reported [53,54] and molecular mechanisms have been proposed [52,60] .…”
Section: Discussionmentioning
confidence: 99%
“…The interplay between membrane curvature and lipid composition has been reported for several proteins, such as the BAR proteins, [48,49] synaptotagmins, [50][51][52][53][54] alpha-synuclein [55][56][57][58] and caveolin. [59] The importance of PIP 2 in synaptotagmin function has been reported [53,54] and molecular mechanisms have been proposed. [52,60] Similarly, the role of PIP lipids, both PIP 2 and PIP 3 , in alpha-synuclein activity was reported.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation