Causes and Treatment of Residual Urine Volume after Orthotopic Bladder Replacement in Women

Jarolı́m, L; Babjuk, Marek; Pecher, S.; Grim, Miloš; Naňka, Ondřej; Tichý, M.; Hanuš, Tomáš; Jansky, Maximiliane

doi:10.1159/000020373

Cited by 11 publications

(1 citation statement)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Following abstract screening and full‐text review, 53 studies ( n = 2740) met our inclusion criteria (Fig. S1) [6,10–62]. Among them, 44 studies comprising 2418 female patients were included in the quantitative synthesis (meta‐analysis).…”

Section: Resultsmentioning

confidence: 95%

Urinary function in female patients after traditional, organ‐sparing and nerve‐sparing radical cystectomy for bladder cancer: a systematic review and pooled analysis

et al. 2023

View full text Add to dashboard Cite

ObjectivesRadical cystectomy (RC) has detrimental effects on the urinary, sexual, and reproductive systems. Approaches to mitigate a decline in postoperative functional quality of life include organ‐preserving and nerve‐sparing variations of RC; however, high‐quality data on gender‐specific outcomes in women remain scarce. We aimed to determine and summarize available data on the urinary, sexual, and health‐related quality of life (HRQOL) outcomes after traditional, reproductive organ preserving (ROPRC) and nerve‐sparing RC (NSRC) for bladder cancer (BCa) in female patients.Evidence AcquisitionThe PubMed, SCOPUS, and Web of Science databases were searched to identify studies reporting on functional outcomes in female patients undergoing RC and urinary diversion for the treatment of BCa. The outcomes of interest were voiding function (for orthotopic neobladder), sexual function, and HRQOL. The following independent variables were derived and included in the meta‐analysis: pooled rate of daytime and nighttime continence/incontinence and intermittent self‐catheterization (ISC) rate. Analyses were performed separately for traditional, organ‐ and/or nerve‐sparing surgical approaches.Evidence SynthesisFifty‐three studies comprising 2,740 female patients (1,201 underwent traditional; 1,539 ‐ organ‐/NS‐sparing, or 264 ‐ NS alone RC) were eligible for qualitative synthesis; 44 studies comprising 2,418 female patients were included in the quantitative synthesis. In women with orthotopic neobladder (ONB) diversion, the pooled rates of daytime continence after traditional, ROPRC and NSRC were 75.2%, 79.3%, and 71.2%, respectively. The pooled rate of nighttime continence after traditional RC was 59.5%; this rate increased to 70.7% and 71.7% in women who underwent ROPRC and NSRC, respectively. The pooled rate of ISC after traditional RC with ONB diversion in female patients was 27.6% and decreased to 20.6% and 16.8% in patients undergoing ROPRC and NSRC, respectively. The use of different definitions and questionnaires in the assessment of postoperative sexual and HRQOL outcomes did not allow a systematic comparison.ConclusionsFemale organ‐ and nerve‐sparing surgical approaches during RC seem to result in improved voiding function. There is a significant need for well‐designed studies exploring sexual and HRQOL outcomes to establish evidence‐based management strategies to support shared decision‐making process tailored toward patient expectations and satisfaction. Understanding expected functional, sexual, and quality of life outcomes is necessary to allow individualized pre‐and postoperative counseling and care delivery in female patients planned for RC.

show abstract

Section: Resultsmentioning

confidence: 95%