Causal role of immune cells in inflammatory bowel disease: A Mendelian randomization study
Haoyu Chen,
Qi Li,
Tianyu Gao
et al.
Abstract:Inflammatory bowel disease (IBD) is characterized by an inflammatory response closely related to the immune system, but the relationship between inflammation and IBD remains unclear. We performed a comprehensive 2-sample Mendelian randomization (MR) analysis to determine the causal relationship between immune cell characteristics and IBD. Using publicly available genetic data, we explored the relationship between 731 immune cell characteristics and IBD risk. Inverse-variance weighting was the primary analytica… Show more
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