Catheter-Based Left Atrial Appendage (Laa) Ligation for the Prevention of Embolic Events Arising From the Laa

Does Left Atrial Appendage Closure with a Cardiac Plug System Reduce the Stroke Risk in Nonvalvular Atrial Fibrillation Patients? A Single‐Center Case Series

“…The LARIAT procedure for percutaneous LAA closure requires both endocardial and epicardial access. The LARIAT Suture Delivery Device is guided over the LAA in an over‐the‐wire approach to slip a prettied suture loop over the appendage under transesophageal echocardiographic guidance to achieve appendage closure …”

Early results with the LARIAT device for left atrial appendage exclusion in patients with atrial fibrillation at high risk for stroke and anticoagulation

“…A new percutaneous closure device (LARIAT ™ snare device; SentreHeart, Inc, Palo Alto, California), has been evaluated recently in animals and used clinically in patients . In an observational, single center study, 81 of 85 patients had complete closure and there were no complications due to the device.…”

Anatomical and electrical remodeling with incomplete left atrial appendage ligation: Results from the LAALA‐AF registry

“…Histological examination of LAA in animals undergoing ligation with Lariat device have demonstrated complete endothelialization within 7 days on the endocardial surface, with no evidence of inflammation or necrosis and complete atrophy of the LAA at 1‐month duration . These observations are probably related to obstruction of epicardial blood flow with the Lariat suture results in complete ischemic necrosis of the distal LAA resulting in atrophy.…”