1999
DOI: 10.1055/s-2007-1013198 View full text |Buy / Rent full text
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Abstract: While experimental and human mapping studies have documented multiple wavelet reentry as the electrophysiological mechanism maintaining atrial fibrillation, recent evidence shows that nearly all paroxysms of atrial fibrillation are initiated by trains of rapid discharges from the pulmonary veins. Radiofrequency catheter ablation targeting these initiating triggers has resulted in an overall 69% freedom from atrial fibrillation at a follow-up of 8 +/- 4 months in a population of 110 patients with paroxysmal atr… Show more

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“…14 This seems to coincide well with the fact that the origin of AF (ie, the origin of frequent triggering of APCs) is commonly located in the LA or at the junction of the pulmonary veins and LA in clinical AF cases. 22,23 This electrophysiological difference in the LA has been reported elsewhere, but this is the first documentation of a difference in the electrophysiological changes over time at several sites in the atria.…”
Section: Heterogeneity In Atrial Remodeling and The Importance Of Thesupporting
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“…14 This seems to coincide well with the fact that the origin of AF (ie, the origin of frequent triggering of APCs) is commonly located in the LA or at the junction of the pulmonary veins and LA in clinical AF cases. 22,23 This electrophysiological difference in the LA has been reported elsewhere, but this is the first documentation of a difference in the electrophysiological changes over time at several sites in the atria.…”
Section: Heterogeneity In Atrial Remodeling and The Importance Of Thesupporting
“…[1][2][3][4][5] However, ectopic beats initiating AF arise from non-PV foci in some patients. 6 The SVC is one of the major sites of these non-PV foci.…”
Section: Discussionmentioning
“…[1][2][3][4][5] However, ectopic beats initiating AF sometimes arise from non-PV foci, such as the superior vena cava (SVC), left atrial (LA) posterior free wall, ligament of Marshall, crista terminalis, and coronary sinus. [6][7][8][9] Because the SVC accounts for the major portion of non-PV foci, 6,10,11 SVC isolation in addition to PV isolation reduces the recurrence of AF.…”
Section: Introductionmentioning
“…[1][2][3][4][5][6][7][8] Since these initial reports, pulmonary vein stenosis (PVS) is a well-known but underreported complication after radiofrequency ablation (RFA). The incidence of PVS could depend on the study definition as well as the ablative technique used and has been reported as high as 42%.…”
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