volume 277, issue 1-2, P73-79 2004
DOI: 10.1016/j.ijpharm.2003.03.003
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Abstract: The role of the newly discovered cysteine protease, cathepsin K, in osteoporosis and rheumatoid arthritis is reviewed. The current development of cathepsin K inhibitors and their targeted delivery using synthetic polymer carriers are discussed. Future challenges and possible strategies to improve these delivery systems are addressed.