Cathartic-induced magnesium toxicity during overdose management

Clinically significant hypermagnesemia in a healthy individual: a rare entity

“…Calcium is especially effective for hypotension, dysarrythmias and respiratory distress and it also enhances the excretion of magnesium. 12,14,15 Commonly used dose for the treatment of hypermagnesemia is 5-10mEq/l of calcium (CaCl 2 ) rapidly intravenous over 30 seconds and repeated as necessary every 5-10 minutes or 100-200mg of calcium over 1-2 hour as 10%calcium gluconate followed by 2-4mEq/kg/hr is given. Vigorous intravenous hydration should be attempted and intravenous furesomide can be given to accelerate magnesium elimination.…”

Breastfeeding Education of Pediatric Residents: A National Survey

“…This is unfortunate since many studies have shown that accurate, appropriate counseling and management improves the rates of breastfeeding initiation and duration if the physician has sufficient knowledge and experience. [9][10][11][12][13] The lack of appropriate breastfeeding education during residency training seems to carry over into practice. A recent survey of 1602 members of the American Academy of Pediatrics concluded that many practicing pediatricians have significant educational needs and gaps of knowledge in the area of breastfeeding education and management.…”

“…Metabolic abnormalities such as electrolyte disturbances may result from stimulation of bowel motility with increased fluid secretion, and electrolyte excretion or hypocalcemia caused by the impairment of parathormone secretion or inhibition of its peripheral effects. 1,9,13 Approximately 30% to 40% of an orally administered dose is rapidly absorbed throughout the small intestine. 13 Decreased gastric motility results in enhanced gut absorption.…”

“…1,9,13 Approximately 30% to 40% of an orally administered dose is rapidly absorbed throughout the small intestine. 13 Decreased gastric motility results in enhanced gut absorption. 8,9 The percentage of the dose absorbed varies with the magnesium load; the smaller the dose, the greater the percentage absorbed.…”

Activated Charcoal in the Treatment of Drug Overdose

“…These include thirst, severe abdominal cramps, fluid and electrolyte abnormalities, hypermagnesaemia and iatrogenic death (Brent et al 1989;Caldwell et al 1987;Farley 1986;Jones et al 1986;Keller et al 1990;McCord & Okun 1987;McNamara et al 1988). …”