Catharanthus roseus flower extract has wound-healing activity in Sprague Dawley rats

Abstract

Background: Catharanthus roseus L (C. roseus) has been used to treat a wide assortment of diseases including diabetes. The objective of our study was to evaluate the antimicrobial and wound healing activity of the flower extract of Catharanthus in rats.

Phytochemical and HPTLC Studies on Fruit Extracts of Momordica cymbalaria Fenzl, a Medicinally Important Plant

“…Saponins cause the leakage of proteins and degradation of cell wall enzymes (Zablotowicz et al, 1996). The presence of phenolic compounds (total phenols and flavonoids) provides pharmacological activities like anticancer (Lin et al, 2008), antioxidant (Khacha-ananda et al, 2013), antimicrobial (Hendra et al, 2011), woundhealing (Nayak and Pinto Pereira, 2006) and antiinflammatory activities (Rathee et al, 2009). Alkaloids were detected in the fruit extracts of M. cymbalaria.…”

Catharanthus roseus: a natural source for the synthesis of silver nanoparticles

“…It is widely growing to 1 m tall at subtropical area. It possesses known antibacterial, antifungal, antibiotic, antioxidant, wound healing and antiviral activities [18][19][20] . Herein, we report for the first time synthesis of silver nanoparticles, reducing the silver ions present in the solution of silver nitrate by the aqueous extract of C. roseus leaf.…”

Synthesis of silver nanoparticles using leaves of Catharanthus roseus Linn. G. Don and their antiplasmodial activities

“…C. roseus exhibited high in vitro antiplasmodial activity, which may be due to the presence of compounds such as alkaloids, terpenoids [33] , flavonoids [34] and esquiterpenes [35] that were previously isolated from the plant. It also possesses known antibacterial, antifungal, antibiotic, antioxidant, wound healing and antiviral activities [36][37][38] . Hence the aim of the present study is to develop a novel approach for the green synthesis of silver nanoparticles using herbal plant C. roseus which has been proven active against the malaria parasite Plasmodium falciparum (P. falciparum).…”