Cashew nut dermatitis. An example of internal-external contact-type hypersensitivity

Ratner, J. H.

doi:10.1001/archderm.110.6.921

Cited by 8 publications

(3 citation statements)

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“…Among other rare findings, Table 3. Proposed terms for cutaneous eruptions related to or imitating the baboon syndrome Internal-external contact type hypersensitivity (Ratner 1974) (47) Mercury exanthem (eczema rubrum) (Nakayama 1983) (2) Baboon syndrome -systemically induced allergic contact dermatitis (Andersen 1984) (1) Nonpigmenting fixed drug eruption (Shelley 1987) (5) Intertriginous drug eruption (Wolf 1992 Sharply demarcated erythema of the gluteal/perianal area and/or V-shaped erythema of the inguinal/perigenital area 3…”

Section: Discussionmentioning

confidence: 99%

Baboon syndrome resulting from systemic drugs: is there strife between SDRIFE and allergic contact dermatitis syndrome?

2004

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The term 'baboon syndrome' (BS) was introduced 20 years ago to classify patients in whom a specific skin eruption resembling the red gluteal area of baboons occurred after systemic exposure to contact allergens. Thereafter, similar eruptions have been reported after systemic exposure to beta-lactam antibiotics and other drugs. In addition to the presentation of 2 of our own cases, we have reviewed and characterized the main clinical and histological aspects of published reports of drug-related baboon syndrome (DRBS) and compared the primary clinical signs from such cases to those found in other distinct drug eruptions. Of approximately 100 published baboon syndrome cases, 50 were identified as drug-induced. Of these, 8 were representatives of systemically induced contact dermatitis (SCD), and 42 were examples of drug eruptions elicited by systemic administration of either oral or intravenous drugs. The main clinical findings included a sharply defined symmetrical erythema of the gluteal area and in the flexural or intertriginous folds without any systemic symptoms and signs. 14 of 42 cases were elicited by amoxicillin, 30 of the 42 patients were male, and latency periods were between a few hours and a few days after exposure. DRBS is a rare, prognostically benign and often underdiagnosed drug eruption with distinct clinical features. The term baboon syndrome, however, does not reflect the complete range of symptoms and signs and is ethically and culturally problematic. Moreover, baboon syndrome is historically often equated with a mercury-induced exanthem in patients with previous contact sensitization. Symmetrical drug-related intertriginous and flexural exanthema, or SDRIFE, specifically refers to the distinctive clinical pattern of this drug eruption, and the following diagnostic criteria are proposed: 1) exposure to a systemically administered drug either at the first or repeated dose (excluding contact allergens); 2) sharply demarcated erythema of the gluteal/perianal area and/or V-shaped erythema of the inguinal/perigenital area; 3) involvement of at least one other intertriginous/flexural localization; 4) symmetry of affected areas; and 5) absence of systemic symptoms and signs.

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Section: Discussionmentioning

confidence: 99%

Baboon syndrome resulting from systemic drugs: is there strife between SDRIFE and allergic contact dermatitis syndrome?

2004

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“…This condition can be observed with and without previous cutaneous sensitization to the hapten but has traditionally been described following topical exposure. Many terms have been applied since it was discovered by Jadassohn in 1895 (1), for example mercury exanthema (2), drug‐induced intertrigo (3), internal–external contact‐type hypersensitivity (4), and systemic contact dermatitis (SCD) (5). Probably, the most creative name was suggested by Andersen et al, as they introduced the term ‘baboon syndrome’(6).…”

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confidence: 99%

Drug‐elicited systemic allergic (contact) dermatitis – update and possible pathomechanisms

Thyssen

Maibach

2008

Contact Dermatitis

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An allergic dermatitis reaction may develop after systemic exposure to a hapten that reaches the skin through haematogenous transport. This condition can be observed with and without previous cutaneous sensitization to the hapten but has traditionally been described following topical exposure. A heterogeneous clinical picture, in combination with limited insight to its pathomechanisms, makes such systemic reactions an area in need of further study. This article summarizes knowledge about systemic dermatitis elicited by drugs, with a special emphasis on possible pathomechanisms. A list of putative pathomechanisms is offered for future research. Literature was examined using PubMed-MEDLINE, EMBASE, Biosis, and Science Citation Index. Based on the literature, it is likely that humoral type 3, delayed-type hypersensitivity, and drug-driven (i.e. p-i concept) reactions are involved. As commonly used terms may be misleading because skin contact is not a prerequisite, we suggest that the term 'systemic allergic dermatitis' should be used in the future.

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“…Five patients developed systemic contact dermatitis after eating large amounts of raw cashews sold in an organic food store . All had a similar clinical presentation of erythematous and vesicular dermatitis involving the palms, axillae, medial aspect of the arms, bathing trunk area, and popliteal fossae.…”

Section: Discussionmentioning

confidence: 99%

Systemic contact dermatitis caused by inhaled cashew oil smoke

2016

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Cashew nut dermatitis. An example of internal-external contact-type hypersensitivity

Cited by 8 publications

References 0 publications

Baboon syndrome resulting from systemic drugs: is there strife between SDRIFE and allergic contact dermatitis syndrome?

Baboon syndrome resulting from systemic drugs: is there strife between SDRIFE and allergic contact dermatitis syndrome?

Drug‐elicited systemic allergic (contact) dermatitis – update and possible pathomechanisms

Systemic contact dermatitis caused by inhaled cashew oil smoke

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