Case report 504

Nikpoor, Nayer; Aliabadi, P.; Poss, Robert; Nusrat, Aterah Z.; Weissman, Barbara N.

doi:10.1007/bf00364048

Cited by 6 publications

(2 citation statements)

References 7 publications

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“…Consequently, operations were carried out to reconstruct pathological fractures or to distinguish the pseudocysts from other bone disorders. [3][4][5]7,13 In recent years, advances in MR imaging have allowed the detection of subarticular pseudocysts before they enlarge enough to cause severe damage. Our present results confirm that large pseudocysts adjacent to knee joints fre- In the present study, we divided the large pseudocysts into two groups according to whether they communicated with the joint cavity.…”

Section: Discussionmentioning

confidence: 99%

“…3,4,[9][10][11][12] Because detecting a connection between large subarticular pseudocysts and the joint cavity is sometimes difficult, opinion has been divided as to whether they arise from primary damage within the bone or by extension from arthritis. [2][3][4][5][6][7]13,14 Thirty years after the first description of large subarticular pseudocysts observed at the proximal part of the tibia, the pathogenesis of this disorder remains obscure. 2 At least, questions remain concerning the development of large pseudocysts, i.e., whether they arise by extension of articular inflammation or from a primary focus within the bone.…”

Section: Introductionmentioning

confidence: 99%

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Development of large pseudocysts adjacent to the knee joint in rheumatoid arthritis. Assessment of radiological and histopathological approaches

Yoshida¹,

Ichinohe²,

Uzuki³

et al. 2002

Modern Rheumatology

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This study examined the pathogenesis of large pseudocysts adjacent to knee joints in rheumatoid arthritis (RA). The radiological and histopathological features of 17 large subarticular pseudocysts in 12 knee joints of 10 patients were analyzed. Nine of the 10 patients were classified as class 2 according to Steinbrocker's functional class. Eight large pseudocysts were located at the lateral femoral condyle, seven were at the proximal part of the tibia, one was at the medial femoral condyle, and one was at the patella. The large pseudocysts were divided into two groups according to whether they did or did not connect with the joint cavity. Serial radiographs revealed that all large pseudocysts in communication with the joint cavity had enlarged gradually over the past several months. They extended from the subarticular area toward the bone marrow. Histopathological findings confirmed that holes allowing communication were located at a transitional zone between the ligament and the hyaline cartilage, and that rheumatoid granulation tissue invaded the large pseudocyst through these holes. The results of this study indicate that large pseudocysts are formed by the extension of articular inflammation. Moreover, repeated extrinsic mechanical stress due to walking and the aggressive inflammatory nature of rheumatoid arthritis play important roles in the formation of large pseudocysts.

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