Cardiovascular toxicity with CTLA‐4 inhibitors in cancer patients: A meta‐analysis
Huiyi Liu,
Lu Fu,
Shuyu Jin
et al.
Abstract:BackgroundWith the emergence of cytotoxic T lymphocyte‐associated protein‐4 (CTLA‐4) inhibitors, the outcomes of patients with malignant tumors have improved significantly. However, the incidence of cardiovascular adverse events has also increased, which can affect tumor treatment. In this study, we evaluated the incidence and severity of adverse cardiovascular events caused by CTLA‐4 inhibitors by analyzing reported trials that involved CTLA‐4 inhibitor therapy.MethodsRandomized clinical trials published in E… Show more
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