Cardiovascular System

Robinson, Wayne F.; Robinson, Nicholas A.

doi:10.1016/b978-0-7020-5319-1.00012-8

Cited by 104 publications

(204 citation statements)

References 0 publications

Supporting

Mentioning

173

Contrasting

Unclassified

Order By: Relevance

“…No marked increases in intimal thickness were detected in the present study. This result differs from findings obtained in humans [22] and dogs [13], in which the thickness of the intima increased with age. Therefore, the risk of aortic rupture in thoroughbred horses might be more strongly related to medial lesions than intimal lesions.…”

Section: Discussioncontrasting

confidence: 99%

“…MPS deposition is generally reported to occur in cystic medial necrosis lesions. Cystic medial necrosis has been suggested to be an underlying cause of aortic rupturing [9, 14, 19]; however, other studies have indicated that it is related to physiological activity [13, 18]. In our study, cystic medial necrosis was first found in a 234-day-old (embryonic) horse.…”

Section: Discussionmentioning

confidence: 46%

See 1 more Smart Citation

Morphometric changes in the aortic arch with advancing age in fetal to mature thoroughbred horses

Endoh

Matsuda

Okamoto

et al. 2017

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

Aortic rupture is a well recognized cause of sudden death in thoroughbred horses. Some microscopic lesions, such as those caused by cystic medial necrosis and medionecrosis, can lead to aortic rupture. However, these microscopic lesions are also observed in normal horses. On the other hand, a previous study of aortic rupture suggested that underlying elastin and collagen deposition disorders might be associated with aortic rupture. Therefore, the purpose of this study was to compare the structural components of the tunica media of the aortic arch, which is composed of elastin, collagen, smooth muscle cells and mucopolysaccharides (MPS), in fetal to mature thoroughbred horses. The percentage area of elastin was greatest in the young horses and subsequently decreased with aging. The percentage area of collagen increased with aging, and the elderly horses (aged ≥20) exhibited significantly higher percentage areas of collagen than the young horses. The percentage area of smooth muscle cells did not change with age. The percentage area of MPS was inversely proportional to the percentage area of elastin. The fetuses exhibited a markedly larger percentage area of MPS than the mature horses. We concluded that the medial changes seen in the aortic arch, which included a reduction in the amount of elastin and increases in the amounts of collagen and MPS, were age-related variations.

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 46%

Morphometric changes in the aortic arch with advancing age in fetal to mature thoroughbred horses

Endoh

Matsuda

Okamoto

et al. 2017

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

show abstract

“…As alterações circulatórias e degenerativas observadas nos pulmões e no fígado desses animais não são específicas da doença, mas achados comuns a quadros de insuficiência cardíaca congestiva esquerda ou mista, que podem ocorrer secundariamente a diferentes cardiopatias (Robinson & Robinson 2016). A pneumonia intersticial vista em ambos os casos, também já descrita, é provável que seja secundária à insuficiência circulatória e não pela ação direta do Parvovirus canino no parênquima pulmonar (Lenghaus et al 1980).…”

Section: Discussionunclassified

“…A cardiomiopatia dilatada secundária a infecção pelo Parvovirus canino deve ser diferenciada das demais cardiomiopatias dilatadas vistas nos cães que, embora as causas permaneçam desconhecidas, fatores genéticos, predisposição familiar em cães de grande porte, deficiência nutricional de taurina e carnitina e hipotireoidismo têm sido reconhecidos como possíveis causas (Robinson & Robinson 2016).…”

Section: Discussionunclassified

Surto de parvovirose cardíaca em filhotes de cães no Brasil

Souto

Olinda

Almeida³

et al. 2018

Pesq. Vet. Bras.

View full text Add to dashboard Cite

RESUMO.-Descrevem-se os aspectos epidemiológicos, clí-nicos, patológicos e imuno-histoquímicos de um surto de parvovirose cardíaca em filhotes de cães. O surto ocorreu em um canil localizado na cidade de Parnamirim, Rio Grande do Norte, região Nordeste do Brasil. De uma ninhada de nove filhotes, um foi natimorto e seis morreram entre 35-57 dias de idade após apresentarem sinais clínicos cardiorrespiratórios com evolução de 10 minutos a três dias. Dos seis filhotes que morreram, dois foram encaminhados para necropsia. No exame macroscópico, ambos os animais apresentaram discreta efusão pericárdica, coração marcadamente globoso, difusa palidez nas superfícies epicárdica e miocárdica e dilatação da cavidade ventricular esquerda. Nos pulmões, observaram-se áreas multifocais avermelhadas na superfície pleural e ao corte fluía líquido espumoso e levemente avermelhado. O fígado estava difusamente aumentado de tamanho, com acentuação do padrão lobular e com áreas pálidas entremeadas por áreas escuras que, ao corte, se aprofundavam ao parênquima. Microscopicamente observou-se miocardite linfohistiocítica, necrosante, associada a fibrose intersticial e corpúsculos de inclu- We describe the epidemiological, clinical, pathological and immunohistochemical aspects of parvoviral myocarditis outbreak in puppies. The outbreak occurred in a kennel located in Parnamirim, Rio Grande do Norte, Northeastern of Brazil. In a litter of nine pups, one was stillbirth and six died between 35-57 days of age after cardiopulmonary clinical signs with evolution of 10 minutes to three days. Of the six puppies that died, two were sent for necropsy. On gross examination, both animals had discreet pericardial effusion, markedly distended heart, diffuse pallor in epicardial and myocardial surfaces and dilation of the left ventricular cavity. The lungs were observed multifocal reddish areas in the pleural surface and at cutting flowed foamed and slightly red liquid. The liver was diffusely increased in size, with lobular standard accentuation and pale areas interspersed with dark areas wich deepened in the parenchyma. Microscopically observed linfohistiocítica myocarditis, necrotizing, associated with interstitial fibrosis and basophilic intranuclear viral inclusions corpuscles in cardiomyocytes. In the lungs there were edema and interstitial pneumonia and in the liver was noted centrilobular to mediozonal degeneration and necrosis associated with congestion and hemorrhage. The diagnosis was confirmed by immunohistochemistry. The parvoviral myocarditis can occasionally occur in puppies of bitches that have not been effectively vaccinated. This clinical form of the disease characterized by cardiorespiratory changes and hyperacute or acute death of the affected animals.INDEX TERMS: Parvoviral myocarditis, newborn dog disease, viral myocarditis, Parvovirus.

show abstract

“…Haemangiosarcoma is a malignant neoplasm that arises from endothelial cells of blood vessels (Robinson and Robinson 2016). It is an aggressive vascular tumour with a high malignant potential (Ravi and Patel 2013).…”

Section: Discussionmentioning

confidence: 99%

Management of tendon haemangiosarcoma in a Bactrian camel (Camelus bactrianus) – a case report

Kvapil

Kastelić²,

Stranjać³

et al. 2017

Acta Vet. Brno

View full text Add to dashboard Cite

An 18-year old intact female Bactrian camel (Camelus bactrianus) was suffering from lameness due to a mass on the right dorsal metacarpal region that caused acute swelling and local skin necrosis. Histology examination and immunohistochemistry of the biopsy material of a mass revealed haemangiosarcoma of the extensor tendons. Three weeks after the biopsy, the tumour was enlarged to 6 cm in diameter and the animal became disabled. The tumour with its associated tendon were resected and the tendon's edges were bridged with a synthetic polytape graft. The camel was fully weight-bearing after the surgery. Two weeks later, the graft was removed due to widespread necrosis. Since the wound was positive for Corynebacterium sp., Acinetobacter iwoffii, Micrococcus sp., Escherichia coli, and Staphylococcus sp., the post-operative antibiotic treatment was prolonged for 28 days. Four months later, the wound healed using daily irrigation and bandaging and the camel walked normally. Nine months after diagnosis, the camel suddenly died without any clinical signs. Metastases of the haemangiosarcoma were found in the liver, lungs, kidneys, brain, meninges, and mediastinum. Exsanguination due to rupture of a liver metastasis was determined as the cause of the death. Haemangiosarcoma is a malignant neoplasm that arises from endothelial cells of blood vessels and tends to be very aggressive. To the author's knowledge, this is the first case report of a metastasizing haemangiosarcoma arising from the lateral extensor tendon in a Bactrian camel.

show abstract

Cardiovascular System

Cited by 104 publications

References 0 publications

Morphometric changes in the aortic arch with advancing age in fetal to mature thoroughbred horses

Morphometric changes in the aortic arch with advancing age in fetal to mature thoroughbred horses

Surto de parvovirose cardíaca em filhotes de cães no Brasil

Management of tendon haemangiosarcoma in a Bactrian camel (Camelus bactrianus) – a case report

Contact Info

Product

Resources

About