Cardiovascular Effects of Ambient Particulate Air Pollution Exposure

Sun, Qinghua; Xiao, Hong; Wold, Loren E.

doi:10.1161/circulationaha.109.893461

Cited by 259 publications

(181 citation statements)

References 118 publications

Supporting

Mentioning

168

Contrasting

Unclassified

Order By: Relevance

“…Our experimental results corroborate with previous findings which illustrated that long exposures to PM air pollution caused the influx of cytokines leading to systemic inflammation. Simultaneously, the markers for oxidative damage were also elevated [36,37]. In the current study, and we have determined the effect of DENPs on platelet numbers and all blood content.…”

Section: Discussionmentioning

confidence: 73%

The possible protective role of quercetin on induced cardiac Oxidative DNA Damage by repeated exposure to diesel exhaust nanoparticles in rats (a histological and immunohistochemical study)

Faruk¹,

Mansy²,

ALasmari³

et al. 2018

J Histol Histopathol

View full text Add to dashboard Cite

Diesel exhaust nanoparticles (DENPs) are gaseous exhaust and one component of particulate matter (PM) air pollution which is found to cause health hazards in humans. Quercetin is widely known for its antioxidant and antitoxic potential. We aimed todetect the protective effect of quercetin in DENP-induced cardio toxicity. Fifty Malealbino rats were divided into two groups,first group (ten rats) divided into two equal subgroups (one receive saline act as control and other receive quercetin,the second group (forty rats)divided equally into two subgroups (one was treated with repeated doses of DENPs [90µg/ rat and 180µg/ rat for 6 days intratracheally every two days] and other treated orally with quercetin (60 mg/kg B.Wt.) 1h prior to DENP exposure,DNA damagewas examined by measureserum8-hydroxydeoguanosine (8-OHdG) levels followed by histological and immunohistochemical studies for nuclear factor-kappa B(NF-κB) expression in heart tissues. Tumor necrosis factor-alpha (TNFα), interleukin-6 (IL-6) and serum level 8-Ohd Gare significantly higher in repeated doses of DENPs than the control group. Pretreatment with quercetin reduced significantly serum level 8-OhdGwhen compared to DENPs group.Cardiac myocytes disruption, vacuolation, inflammation and wide separation of its fibers in contrast to control group. Myocyteinflammations were significantly decreased with quercetin group compared with control group (decrease NF-κBimmunostaining). The present work yields experimentalevidence that quercetin can reduce oxidative DNA damage and inflammation induced by DENPs, so suggested that quercetin possible cardioprotective effect against DENPs.

show abstract

Section: Discussionmentioning

confidence: 73%

The possible protective role of quercetin on induced cardiac Oxidative DNA Damage by repeated exposure to diesel exhaust nanoparticles in rats (a histological and immunohistochemical study)

Faruk¹,

Mansy²,

ALasmari³

et al. 2018

J Histol Histopathol

View full text Add to dashboard Cite

show abstract

“…A report of the World Health Organization (WHO [7]) and a recent result of (Sun et al [8]), indicate a 0.11% increase in mortality due to cardiovascular or respiratory diseases, for a 10μg/m 3 increase in the daily average of PM 10 . With respect to the correlation between pollution and emergency hospital admissions, at the European level, (Blangiardo et al [9]) reported that a 10μg/m 3 daily increase in PM 10 concentration produces a 0.9%, 0.8% and 1.3% increase in admissions, in London, due to cardiac diseases, myocardial infarction and respiratory disease, respectively.…”

Section: Environment-related Decision Support For Health Risk Assessmentmentioning

confidence: 99%

Smart cities management by integrating sensors, models and user generated contents

Candelieri¹,

Archetti²,

Giordani³

et al. 2013

WIT Transactions on Ecology and the Environment

View full text Add to dashboard Cite

This paper presents a further innovation of the collaborative decision support network LENVIS, developed in the homonymous European FP7 project (Localized ENVIronmental Services for all, www.lenvis.eu). The system is aimed at supporting water and air quality management and assessing the impact on health computed as emergency hospital admissions. LENVIS has been designed according to the Internet of Services paradigm: several web services, such as sensors data integrators, geographical information systems, predictive and simulation models, and data analytics tools, have been suitably combined to provide complex applications to different stakeholders. LENVIS has been already integrated with popular social networking platforms as Facebook, Twitter and Linkedin ensuring that its information can be assessed seamlessly during a user's regular internet browsing activities and that the user generated contents can be processed by LENVIS analytics. The experiences referred to in this paper are from Milan, a city in Northern Italy with severe pollution problems, mostly due to Particulate Matters (PM), and three cities in Portugal, where the quality of bathing water affects the way in which population uses water resources.

show abstract

“…De estas, las de mayor interés son las partículas PM10 (partículas ≤ 10 micrómetros de diámetro), ya que estas, pueden penetrar profundamente en los pulmones, y algunas pueden incluso entrar en el torrente sanguíneo (EPA, 2012). La composición química de las partículas, es uno de los factores que determina el riesgo a la salud, además de su tamaño y área superficial (Sun et al, 2010). La "partícula" es un término que se emplea para describir cualquier material sólido o líquido dividido finamente, que es dispersado y arrastrado por el aire y que tiene un tamaño que varía entre 0.0002 y 500 μm.…”

Section: Introductionunclassified

Niveles de Partículas Suspendidas Totales (PST), PM10 y PM2.5 y su Relación en Lugares Públicos de la Ciudad Riohacha, Caribe Colombiano

2013

View full text Add to dashboard Cite

ResumenSe determinaron las concentraciones de partículas suspendidas totales (PST) y partículas menores de 10 y 2.5 micrómetros (PM10 y PM2.5) en la zona urbana del municipio de Riohacha, Colombia. Los instrumentos utilizados fueron un muestreador de alto volumen para PST y PM10 y un muestreador de bajo volumen (Partisol) para las partículas PM2.5, todo en seis estaciones de monitoreo. Los resultados mostraron que el promedio de la concentración de PM10 varió desde 43,69 a 19,47 µg/m3, las PST de 86,02 a 27,38 µg/m3 y las PM2.5 mostraron un promedio de 14.57 µg/m3. Las relaciones PM10/PST variaron desde 0,50 a 0.68. Las seis estaciones presentaron buena correlación PST/PM10 (R = 0,795). Las PST pueden implicar presencia de partículas PM10 en el área urbana esta ciudad, pero las concentraciones de PM10 no necesariamente indican presencia de partículas PM2.5 (R= 0,035). Los resultados de correlación de PM10/PST son similares a estudios realizados en otras zonas urbanas de Colombia y de otros países.Palabras clave: partículas en suspensión, medio ambiente, calidad del aire, PST, PM10, PM2.5 Levels of total suspended particles (TSP), PM10 and PM2.5 and their relationship in public places of the city Riohacha, Colombian Caribbean AbstractThe concentrations of total suspended particles (TSP) and particles with size below 10 and 2.5 micrometers (PM10 and PM2.5) in the urban area of the city of Riohacha in Colombia were determined. The instruments used were a high-volume sampler for TSP and PM10 and a low-volume sampler (Partisol) for PM2.5, all in six monitoring stations. The results showed that the average PM10 concentrations ranged from 43.69 to 19.47 µg/m3, the PST ranged from 86.02 to 27.38 µg/m3 and the average for PM2.5 was 14.57 µg/m3. Relations PM10/PST ranged from 0.50 to 0.68. The six stations showed good correlation PST/PM10 (R=0.795). The PST can imply the presence of PM10 particles in the urban area of this city but PM10 concentrations not necessarily indicate the presence of PM2.5 particles (R=0.035). The results for the correlation PM10/PST are similar to studies conducted in other urban areas of Colombia and of other countries.

show abstract

Cardiovascular Effects of Ambient Particulate Air Pollution Exposure

Cited by 259 publications

References 118 publications

The possible protective role of quercetin on induced cardiac Oxidative DNA Damage by repeated exposure to diesel exhaust nanoparticles in rats (a histological and immunohistochemical study)

The possible protective role of quercetin on induced cardiac Oxidative DNA Damage by repeated exposure to diesel exhaust nanoparticles in rats (a histological and immunohistochemical study)

Smart cities management by integrating sensors, models and user generated contents

Niveles de Partículas Suspendidas Totales (PST), PM10 y PM2.5 y su Relación en Lugares Públicos de la Ciudad Riohacha, Caribe Colombiano

Contact Info

Product

Resources

About