Cardiac Tumors

Hoffmeier, A.; Sindermann, Jürgen R.; Scheld, Hans H.; Martens, Sven

doi:10.3238/arztebl.2014.0205

Cited by 144 publications

(119 citation statements)

References 34 publications

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“…Primary cardiac tumors are rare neoplasms with an autopsy incidence between 0.001% and 0.3% [1-3] . Approximately 75-80% of primary cardiac tumors are benign, and of those, more than half are myxomas [1-6] .…”

Section: Introductionmentioning

confidence: 99%

Biatrial Approach Provides Better Outcomes in the Surgical Treatment of Cardiac Myxomas

Yüksel¹,

Saba²,

Velioğlu³

et al. 2016

Brazilian Journal of Cardiovascular Surgery

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ObjectiveWe aimed to present clinical features, surgical approaches, importance of surgical technique and long-term outcomes of our patients with cardiac myxoma who underwent surgery.MethodsWe retrospectively collected data of patients with cardiac myxoma who underwent surgical resection between February 1990 and November 2014. Biatrial approach is the preferred surgical method in a large proportion of patients that are operated due to left atrial myxoma because it provides wider exposure than the uniatrial approach. To prevent recurrence during surgical resection, a large excision is made so as to include at least 5 mm of normal area from clean tissue around the tumor. Moreover, special attention is paid to the excision that is made as a whole, without digesting the fragment of tumor with gentle dissections.ResultsForty-three patients (20 males, mean age of 51.7±8.8 years) were included. Most common symptom was dyspnea (48.8%). Tumor was located in the left atrium in 37 (86%) patients. Resections were achieved via biatrial approach in 34 patients, uniatrial approach in 8 patients, and right atriotomy with right ventriculotomy in 1 patient. One patient died due to low cardiac output syndrome in the early postoperative period. Mean follow-up time was 102.3±66.5 months. Actuarial survival rates were 95%, 92% and 78% at five, 10 and 15 years, respectively. Recurrence was observed in none of the patients during follow-up.ConclusionAlthough myxomas are benign tumors, due to embolic complications and obstructive signs, they should be treated surgically as soon as possible after diagnosis. To prevent recurrence, especially in cardiac myxomas which are located in left atrium, preferred biatrial approach is suggested for wide resection of the tumor and to avoid residual tumor.

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Section: Introductionmentioning

confidence: 99%

Biatrial Approach Provides Better Outcomes in the Surgical Treatment of Cardiac Myxomas

Yüksel¹,

Saba²,

Velioğlu³

et al. 2016

Brazilian Journal of Cardiovascular Surgery

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“…The disease usually progresses without symptoms until the tumor burden compromises hemodynamic stability, and/or causes systemic derangement, or regional metastases arise 7. Symptoms may be nonspecific, such as a mild increase in temperature, weight loss, exhaustion, muscle pain, night sweats, and cough 8.…”

Section: Discussionmentioning

confidence: 99%

“…Symptoms may be nonspecific, such as a mild increase in temperature, weight loss, exhaustion, muscle pain, night sweats, and cough 8. Nonetheless, depending on the site of the tumor and its extension to the neighboring tissue infiltration, characteristic cardiac symptoms or signs will be present; such as angina, dyspnea, arrhythmias, stroke, and sudden cardiac arrest 7 , 9. Pericardial effusion and cardiac tamponade are frequent 10…”

Section: Discussionmentioning

confidence: 99%

Cardiac angiosarcoma: an unexpected diagnosis

Crenitte¹,

Galvão²,

Bernardi³

et al. 2014

ACR

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Cardiac angiosarcoma is a rare entity. The incidence through autopsy findings ranges between 0.001% and 0.03%. The disease usually presents with non-specific symptoms, although asymptomatic cases are frequent; therefore, diagnosis is unexpected and consequently delayed. The authors report the case of a middle-aged man with a recent onset cough and dyspnea. He sought medical care several times without receiving a definite diagnosis until a plain chest radiography was taken showing a mediastinal enlargement, which was the reason why he was hospitalized for clinical investigation. During the diagnostic workup, an echodopplercardiogram and a thoracic computed tomography were performed, showing a heterogeneous soft-tissue mass infiltrating the pericardium and the anterior atrial wall. Multiple and scattered pulmonary nodules were also present. A pulmonary nodule was biopsied, which revealed an angiosarcoma. The clinical features added to the radiological and histological findings permitted the diagnosis of right atrial angiosarcoma. The authors highlight the unexpected pattern in the presentation of cardiac tumors.

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“…As the survival times for primary osteosarcoma continue to improve, late stage complications will undoubtedly become more prevalent in the future [2, 3]. …”

Section: Introductionmentioning

confidence: 99%

Osteosarcoma of the lower limb metastasized to the septum and right side of the heart: a case report

Osati

Kaijage²,

Muta

et al. 2017

J Med Case Reports

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BackgroundMetastatic cardiac tumors are far more common than primary tumors. Although the hematogenous spread of osteosarcoma is well known, the imaging findings of cardiovascular involvement by osteosarcoma are seldom reported and can be difficult to recognize.Case presentationA 21-year-old man of African descent presented to our center complaining of shortness of breath, awareness of heart beats, easy fatigability, swelling of lower limbs, and left-side chest discomfort for the past 6 months getting worse for the last 3 months prior to his third readmission. In 2004 he was admitted with the diagnosis of osteosarcoma of his left calcaneus bone confirmed by bone biopsy and treated at an oncology center with several cycles of radiotherapy and chemotherapy; he was declared cured after 5 years of annual clinical and radiological skeletal survey follow-ups. In the current admission, a physical examination revealed bilateral lower limb swelling, pansystolic murmur on the left side of his sternum at fourth intercostal space (tricuspid area) grade three, hepatomegaly with a liver span of 17 cm, and a positive fluid test and shifting dullness.ConclusionsThis case report presents a 21-year-old man with relapsed osteosarcoma manifesting as metastatic lesions to his right ventricle encroaching on his interventricular septum, which was identified by transthoracic/transesophageal echocardiography computed tomography scan and cardiac magnetic resonance imaging.

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Cardiac Tumors

Abstract: Patients with cardiac tumors should undergo surgery in a timely fashion in a specialized center. This holds for both malignant and benign tumors, particularly for atrial myxoma, which can cause serious secondary complications by embolization.

Cited by 144 publications

References 34 publications

Biatrial Approach Provides Better Outcomes in the Surgical Treatment of Cardiac Myxomas

Biatrial Approach Provides Better Outcomes in the Surgical Treatment of Cardiac Myxomas

Cardiac angiosarcoma: an unexpected diagnosis

Osteosarcoma of the lower limb metastasized to the septum and right side of the heart: a case report

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