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Cited by 3 publications
(5 citation statements)
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References 13 publications
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“…However, she continued to have symptomatic anaemia and was eventually diagnosed with Burkitt’s lymphoma Not reported Harris et al [ 45 ] CD 17 years ( N = 1) Not reported Two days post-infusion, a patchy, brown discolouration of the skin surrounding the initial cannula site was reported. This case represents one of three occurrences of skin staining secondary to iron extravasation recognised within the department between December 2014 and August 2016 Harris et al [ 50 ] IBD 16–17 years ( N = 3) Case 1: Hb increased from 109 to 111–127 g/L after 1 month; case 2: Hb increased from 115 to 121–132 g/L after 8 weeks; case 3: iron 8 μmol/L and TSAT 13% pre-FCM and remained low 6 weeks after the second infusion (iron 5 μmol/L and TSAT 11%) All three patients experienced hypophosphataemia Hönemann et al [ 46 ] Post-traumatic anaemia patient who refused blood transfusion 17 years ( N = 1) Improvement in Hb concentration (4.2 to 11.1 g/dL after 17 days) No AEs reported Joseph et al [ 47 ] IRIDA and at risk of hypersensitivity reactions Adolescent (age not given) ( N = 1) A 12-step FCM desensitisation protocol resulted in tolerated FCM and corrected anaemia Not reported Pérez-Ferrer et al [ 48 ] Cardiac surgery and factor VII deficiency, parents did not consent to blood transfusion 5 years ( N = 1) Improvement in Hb (12.5 to 14.5 g/dL) and Ht (36.6 to 47.1%) within 12 days of erythropoietin and FCM treatment; no transfusion of blood products required Not reported Shrinkhal et al [ 49 ] Anaemic retinopathy, megaloblastic anaemia with thrombocytopenia 16 years ( N = 1) Changes in iron status not reported; retinal haemorrhage spontaneously resolved with clearance of fovea and the patient gained vision Not reported Others ...…”
Section: Resultsmentioning
confidence: 99%
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“…However, she continued to have symptomatic anaemia and was eventually diagnosed with Burkitt’s lymphoma Not reported Harris et al [ 45 ] CD 17 years ( N = 1) Not reported Two days post-infusion, a patchy, brown discolouration of the skin surrounding the initial cannula site was reported. This case represents one of three occurrences of skin staining secondary to iron extravasation recognised within the department between December 2014 and August 2016 Harris et al [ 50 ] IBD 16–17 years ( N = 3) Case 1: Hb increased from 109 to 111–127 g/L after 1 month; case 2: Hb increased from 115 to 121–132 g/L after 8 weeks; case 3: iron 8 μmol/L and TSAT 13% pre-FCM and remained low 6 weeks after the second infusion (iron 5 μmol/L and TSAT 11%) All three patients experienced hypophosphataemia Hönemann et al [ 46 ] Post-traumatic anaemia patient who refused blood transfusion 17 years ( N = 1) Improvement in Hb concentration (4.2 to 11.1 g/dL after 17 days) No AEs reported Joseph et al [ 47 ] IRIDA and at risk of hypersensitivity reactions Adolescent (age not given) ( N = 1) A 12-step FCM desensitisation protocol resulted in tolerated FCM and corrected anaemia Not reported Pérez-Ferrer et al [ 48 ] Cardiac surgery and factor VII deficiency, parents did not consent to blood transfusion 5 years ( N = 1) Improvement in Hb (12.5 to 14.5 g/dL) and Ht (36.6 to 47.1%) within 12 days of erythropoietin and FCM treatment; no transfusion of blood products required Not reported Shrinkhal et al [ 49 ] Anaemic retinopathy, megaloblastic anaemia with thrombocytopenia 16 years ( N = 1) Changes in iron status not reported; retinal haemorrhage spontaneously resolved with clearance of fovea and the patient gained vision Not reported Others ...…”
Section: Resultsmentioning
confidence: 99%
“…Findings on the efficacy of FCM in children and/or adolescents were reported in 27 of the 33 publications (Table 1 ) [ 21 28 , 30 33 , 36 – 44 , 46 48 , 50 , 51 , 53 ]. In 26 of the 27 publications that included efficacy results, FCM treatment (in most cases a single dose) was associated with improvement in anaemia and/or different iron status parameters, including improvements in levels of haemoglobin (22 publications), ferritin (12 publications), mean corpuscular volume (10 publications), iron (six publications) and transferrin saturation (five publications) (Table 1 ).…”
Section: Resultsmentioning
confidence: 99%
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“…Congenital deficiency of coagulation factor VII, VIII or von Willebrand factor further increases the risk of bleeding and therefore, blood transfusion. [ 16 17 18 ] Furthemore, children with cardiac lesions involving systolic flow abnormalities are at increased risk of developing qualitative platelet dysfunction than those with diastolic flow abnormalities. [ 19 ] The exposure to extracorporeal circuit also leads to the development of qualitative and quantitative platelet abnormalities, coagulation factor deficiencies, and hypofibrinogenemia.…”
Section: Challenges For Blood Conservation In Pediatric Age Groupmentioning
confidence: 99%