Cardiac Hemodynamics in Men Versus Women During Acute ST-Segment Elevation Myocardial Infarction

Dreyer, Rachel P.; Beltrame, John F.; Neil, Christopher; Air, Tracy; Tavella, Rosanna; Hoffmann, Bernadette; Pati, P.; Fiore, David Di; Arstall, Margaret A.; Zeitz, Chris

doi:10.1016/j.amjcard.2013.03.007

Cited by 10 publications

(9 citation statements)

References 29 publications

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“…in-hospital major bleeding 13 in-hospital major bleeding (PCi) 42 30-day major bleeding 13 3-year major bleeding 13 in-hospital mortality 13,25 in-hospital mortality (steMi) 37 in-hospital mortality (PCi) 42 30-day mortality 5,13,15,30 1-year mortality 38 3-year mortality 13 5-year mortality 39 10-year mortality 39 in-hospital re-infarction 13 in-hospital re-infarction (PCi) 42 30-day re-infarction 13 30-day re-infarction (steMi) 5 3-year re-infarction 13 1-year acs rehospitalization 44 1-year ami rehospitalization 38 30-day rehospitalization 43 in-hospital, 30-day, or 3-year tvr for ischemia 13 in-hospital, 30-day, or 3-year stroke 13 higher stress during recovery 46 1-Month angina 46 1-Month lower quality of life 46,47 1-Month worse mental health 46 6-Month, 12-month lower hrql 47 Canada; $75 years 48 30-day mortality U.S.…”

Section: Discussionmentioning

confidence: 99%

“…13 In the study on cardiac hemo dynamics, women with STEMI were found to have a higher 30day reinfarction rate than men. 5 Recovery. Worse postAMI recovery experienced by women might be explained in part by a lower quality of life and higher levels of perceived stress.…”

Section: -Month Mortality (Pci) 42mentioning

confidence: 99%

“…This increased left ventricular filling pres sure was independent of age, hypertension status, or infarct size, suggesting that it is largely gender dependent. 5 These pathophysiological differences may be associated with dif ferences in ACS/MI symptomology and with options for revascularization. 6,7…”

Section: Introductionmentioning

confidence: 99%

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Acute Coronary Syndromes in Women: Recent Treatment Trends and Outcomes

Graham

2016

Clin Med Insights Cardiol

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In the USA and internationally, women experience farranging differences with respect to acute coronary syndrome (ACS) and myocardial infarction (MI). Women suffer from more comorbidities than men, such as smoking, obesity, hypertension, diabetes, and poor mental health. They some-times exhibit atypical MI presentation symptoms and are overall less likely to present with chest pain. Women are more likely than men to encounter delays between the onset of symptoms and arrival at the hospital or to guideline treatment. The use of various surgical and pharmacological treatments, including revascularization approaches, also differs. Women, on average, have worse outcomes than men following MI, with more complications, higher mortality rates, and poorer recovery. Internationally, outcomes are similar despite various differences in health care and culture in non-US countries. In this review, we detail differences regarding ACS and MI in women, describing their complex correlations and discussing their possible causes. Educational approaches that are tailored to women might help to reduce the incidence of ACS and MI, as well as outcomes following hospitalization. Although outcomes following acute MI have been improving over the years, women may require special consideration in order to see continued improvement.

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Section: Discussionmentioning

confidence: 99%

Section: -Month Mortality (Pci) 42mentioning

confidence: 99%

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Acute Coronary Syndromes in Women: Recent Treatment Trends and Outcomes

Graham

2016

Clin Med Insights Cardiol

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“…While there have been studies to suggest that hemodynamic measures can predict 30-day mortality and infarct size (IS), the evidence of the prognostic value of hemodynamic measures in STEMI patients is limited [ 22 ], partly because right heart catheterization is no longer performed due to associated risks. LV end-diastolic pressure is frequently measured at PCI, however, and has been shown to be an independent predictor of in-hospital death, cardiogenic shock and HF [ 23 ].…”

Section: In-hospital Coursementioning

confidence: 99%

Risk assessment in patients with an acute ST-elevation myocardial infarction

et al. 2016

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ST-elevation myocardial infarction (STEMI) is one of the leading causes of mortality and morbidity worldwide. While the survival after acute STEMI has considerably improved, mortality rate still remains high, especially in high-risk patients. Survival after acute STEMI is influenced by clinical characteristics such as age as well as the presence of comorbidities. However, during emergency care increasing access to tools such as the electrocardiogram, chest x-ray and echocardiography can provide additional information helping to further risk stratify patients. In the invasive setting, this can also include coronary angiography, invasive hemodynamic recordings and angiographic assessments of coronary flow and myocardial perfusion. We outline the common investigations used in STEMI and their role in risk assessment of patients with an acute STEMI.

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“…While filling pressures are suboptimal correlates of the volume status, they are often used to guide fluid resuscitation [2]. Moreover, pulmonary capillary wedge pressure has been found to be a predictor of adverse outcomes following acute myocardial infarction [3,4]. In the contemporary cardiac surgical arena the PAC provides important information about the hemodynamic performance of the right ventricle and the resistance in the pulmonary vascular bed.…”

Section: Introductionmentioning

confidence: 99%